P38alpha MAP Kinase Antibody – Mouse Monoclonal

The MAPKs (Mitogen-Activated Protein Kinases) are protein-serine/threonine kinases which signal transduction pathways that control intracellular events including acute responses to hormones and major developmental changes in organisms. Upon activation, p38 alpha MAPK translocates into the nucleus where it phosphorylates one or more nuclear substrates, effecting transcriptional changes and other cellular processes involved in cell growth, division, differentiation, inflammation, and death. p38 alpha MAPK is activated by chemical stress inducers including hydrogen peroxide, heavy metals, anisomycin, sodium salicylate, lipopolysaccharide, and biological stress signals such as tumor necrosis factor, interleukin-1, ionizing and UV irradiation, hyperosmotic stress and chemotherapeutic drugs.

Small volumes of anti-p38alpha MAP Kinase antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS190487 is an antibody targeting p38alpha MAP Kinase. Also known as Anti-p38alpha MAP Kinase Monoclonal Antibody. Host: Mouse.