HSC70/HSP 73 Antibody – Mouse Monoclonal

Hsp70 genes, members of a multigene family, encode heat-inducible 70kDa heatshock proteins that function as molecular chaperones. They have been identified in most organelles of eukaryotic cells as well as in bacteria. The N-terminus of Hsp70 binds ATP with high affinity and the Cterminus binds proteins and polypeptides. When cells are subjected to metabolic stress, Hsp70 is expressed. Hsp70 shares >90% sequence homology with Hsc70. Constitutively expressed Hsc70 forms a stable complex with the highly inducible Hsp70 in cells following heat shock. This interaction is regulated by ATP. Research on Hsc70 suggests that it plays a role in facilitating the recovery of centrosomal structure and function after heat shock.

Small volumes of anti-Hsc70/Hsp 73 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS190514 is an antibody targeting Hsc70/Hsp 73. Also known as Anti-Hsc70/Hsp73 Monoclonal Antibody. Reactive in Human, mouse, rat. Host: Mouse.