HSP25/HSP27 Antibody – Mouse Monoclonal

Hsp25 is the mouse homologue of human Hsp27, a member of the small heat shock protein family comprised of proteins of ~15->30kDa. Oligomers of Hsp27 consist of as many as 8-40 Hsp27 monomers; large oligomers have high chaperone activity whereas dimers have no chaperone activity. Hsp27 is localized to the cytoplasm of unstressed cells but redistributes to the nucleus in response to stress where it may stabilize DNA and/or the nuclear membrane. It can be rapidly phosphorylated in response to physiological stimuli, and, therefore, has been suggested as an important intermediate in second messengermediated signaling pathways. Hsp27 appears to be involved in cell differentiation and may play a role in termination of cell growth.

Small volumes of anti-Hsp25/Hsp27 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS190585 is an antibody targeting Hsp25/Hsp27. Also known as Anti-Hsp25/Hsp27 Monoclonal Antibody. Reactive in Human, mouse, rat, bovine, canine, guinea pig, hamster. Host: Mouse.