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SUR1 / SUR2B Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS190656

Sulfonylurea receptors (SUR) are membrane proteins that are molecular targets of the sulfonylurea class of antidiabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. SUR proteins are subunits of the inward-rectifier… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SUR1 / SUR2B, Monoclonal Antibody
Full Product Name
SUR1 / SUR2B Monoclonal Antibody
Product Synonym Names
Anti-SUR1/SUR2B
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Specificity
This antibody recognizes mouse and rat SUR1 and SUR2B.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freezing and thawing.
Molecular Weight
174,306 Da
Antigen
Fusion protein corresponding to aa 1503-1545 (VHTILTADLVIVMKRGNILEYDTPESLLA QEDGVFASFVRADM, cytoplasmic C-terminus) of rat SUR2B (accession no. Q63563-2).
Positive Control
Mouse brain lysate.
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Applications Tested/Suitable for anti-SUR1 / SUR2B antibody
Immunoblot (IB)
Application Notes for anti-SUR1 / SUR2B antibody
Immunoblotting: Use at 1-2ug/ml. A band of ~175kDa is detected. Smaller fragments, most likely due to cleavage products, are also detected.

Other Notes

Small volumes of anti-SUR1 / SUR2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SUR1 / SUR2B purchase

MBS190656 is an antibody targeting SUR1 / SUR2B. Also known as SUR1 / SUR2B Monoclonal Antibody. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SUR1 / SUR2B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
sulfonylurea receptor 2B
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 9
NCBI Official Symbol
Abcc9
NCBI Official Synonym Symbols
Sur2
UniProt Protein Name
ATP-binding cassette sub-family C member 9
UniProt Synonym Protein Names
Sulfonylurea receptor 2
UniProt Gene Name
Abcc9
UniProt Synonym Gene Names
Sur2
UniProt Entry Name
ABCC9_RAT
NCBI Protein Information
ATP-binding cassette sub-family C member 9

NCBI Summary for SUR1 / SUR2B

ATP-sensitive potassium channel subunit that confers ATP sensitivity and acts as receptor for sulfonylurea; may play a role in mesangial cell contractility in response to calcium ion transients [RGD, Feb 2006]

UniProt Comments for SUR1 / SUR2B

Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-SUR1 / SUR2B antibody

 Organ/Tissue Name  Pubmed Publications
 Colon Antibodies  >4 publications with SUR1 / SUR2B and Colon
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