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Pannexin-2 (PANX2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS190927

The Pannexin gene family encodes a class of putative gap junction proteins. Pannexins are highly conserved in invertebrates and mammals. Mammalian Pannexin-1 and Pannexin-3 are closely related, while Pannexin-2 is more distantly related. Pannexin-2 is a… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Pannexin-2 (PANX2), Monoclonal Antibody
Full Product Name
Pannexin-2 Monoclonal Antibody
Product Gene Name
Product Synonym Names
Anti-Pannexin-2
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Specificity
This antibody recognizes rat Pannexin-2.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
Molecular Weight
Predicted molecular weight is 70kDa.
OMIM
608421
Antigen
Fusion protein corresponding to aa 11-664 (extracellular and cytoplasmic domains) of rat Pannexin-2 (accession no.P60571).
Positive Control
Rat brain lysate
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Applications Tested/Suitable for anti-PANX2 antibody
Immunoblot (IB)
Application Notes for anti-PANX2 antibody
Immunoblotting: Use at 1ug/ml.

Other Notes

Small volumes of anti-PANX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PANX2 purchase

MBS190927 is an antibody targeting PANX2. Also known as Pannexin-2 Monoclonal Antibody. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PANX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pannexin-2 isoform 2
NCBI Official Synonym Full Names
pannexin 2
NCBI Official Symbol
PANX2
NCBI Official Synonym Symbols
PX2; hPANX2
UniProt Protein Name
Pannexin-2
Protein Family
UniProt Gene Name
PANX2
UniProt Entry Name
PANX2_HUMAN
NCBI Protein Information
pannexin-2

NCBI Summary for PANX2

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
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UniProt Comments for PANX2

PANX2: Structural component of the gap junctions and the hemichannels. Belongs to the pannexin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 22q13.33

Cellular Component: cytoplasm; gap junction; integral to membrane; plasma membrane

Molecular Function: gap junction hemi-channel activity

Biological Process: ion transport; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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