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Glutathione Reductase (GSR) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS190998

Legionella pneumophila are Gram- negative aerobic coccobacilli isolated from natural and artificial fresh water reservoirs. The outer membrane of L. pneumophila is comprised of a unique lipopolysaccharide (LPS) which is less endotoxic than enterobacterial… More details

$510 / 0.2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glutathione Reductase (GSR), Monoclonal Antibody
Full Product Name
Glutathione Reductase
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1kappa
Host
Mouse
Form/Format
200ug/clone in phosphate-buffered saline, pH 7.4
Specificity
These antibodies recognize human glutathione reductase. They do not cross-react with yeast glutathione reductase.
Preparation and Storage
These antibodies are stable for at least one (1) year at -20 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Molecular Weight
47,267 Da
OMIM
X15722 mRNA
3D Structure
ModBase 3D Structure for P00390
Antigen
Recombinant human glutathione reductase purified from E Coli expressing the human glutathione reductase gene (aa 44-522).
Applications Tested/Suitable for anti-GSR antibody
ELISA (EIA)
Application Notes for anti-GSR antibody
ELISA: Titration of glutathione reductase MAbs with glutathione reductase at 3ug/ml on the wells.
ELISA Pairs: Both of these antibodies function as capture and detection antibodies at 1ug/ml.
Dilute in PBS or medium that is identical to that used in the assay system.

Testing Data of anti-GSR antibody

Mouse Anti-GSR Monoclonal Antibody – Cat# MBS190998

Testing Data of anti-GSR antibody

Mouse Anti-GSR Monoclonal Antibody, Testing Data – Cat# MBS190998

Testing Data of anti-GSR antibody

Mouse Anti-GSR Monoclonal Antibody, Testing Data – Cat# MBS190998

Testing Data of anti-GSR antibody

Mouse Anti-GSR Monoclonal Antibody, Testing Data – Cat# MBS190998

Other Notes

Small volumes of anti-GSR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSR purchase

MBS190998 is an antibody targeting GSR. Also known as Glutathione Reductase. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GSR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glutathione reductase, mitochondrial isoform 1
NCBI Official Synonym Full Names
glutathione-disulfide reductase
NCBI Official Symbol
GSR
NCBI Official Synonym Symbols
HEL-75; HEL-S-122m
UniProt Protein Name
Glutathione reductase, mitochondrial
Protein Family
UniProt Gene Name
GSR
UniProt Synonym Gene Names
GLUR; GRD1; GR; GRase
NCBI Protein Information
glutathione reductase, mitochondrial

NCBI Summary for GSR

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]
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UniProt Comments for GSR

GSR: a class-I pyridine nucleotide-disulfide oxidoreductase. Maintains high levels of reduced glutathione in the cytosol. Alternative initiation results in a mitochondrial and a cytoplasmic isoform.

Protein type: EC 1.8.1.7; Other Amino Acids Metabolism - glutathione; Oxidoreductase

Chromosomal Location of Human Ortholog: 8p12

Cellular Component: cytosol; mitochondrial matrix

Molecular Function: electron carrier activity; glutathione-disulfide reductase activity

Biological Process: nucleobase, nucleoside and nucleotide interconversion; response to reactive oxygen species
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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