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JunD Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS191040

JunD protein encoded by this intronless gene is a member of the JUN family and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation… More details

$465 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
JunD, Polyclonal Antibody
Full Product Name
JunD (Phospho-Ser255)
Product Gene Name
anti-JunD antibody
Clonality
Polyclonal
Host
Rabbit
Form/Format
100ul at 1.0mg/ml in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Affinity-purified on phosphopeptide; non-phosphopeptide- reactive antibodies were removed by chromatography on non-phosphorylated peptide.
Specificity
This antibody detects endogenous human, mouse, and rat JunD only when phosphorylated at serine 255.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Can be stored at 4 degree C for short-term use.
Molecular Weight
35,174 Da
OMIM
X56681 mRNA
3D Structure
ModBase 3D Structure for P17535
Antigen
Peptide sequence that includes phosphorylation site of serine 255 (G-E-S(p)-P-P) derived from human JunD and conjugated to KLH.
Applications Tested/Suitable for anti-JunD antibody
Immunoblotting (IB), Immunohistochemistry (IHC)
Application Notes for anti-JunD antibody
Immunoblotting: use at dilution of 1:500-1:1,000. A band of ~38kDa is detected.
Immunohistochemistry: use at dilution of 1:50- 1:100.
Dilute in PBS or medium that is identical to that used in the assay system.

Immunohistochemistry (IHC) of anti-JunD antibody

Rabbit Anti-JunD Polyclonal Antibody – Cat# MBS191040

Testing Data of anti-JunD antibody

Rabbit Anti-JunD Polyclonal Antibody, Testing Data – Cat# MBS191040

Other Notes

Small volumes of anti-JunD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JunD purchase

MBS191040 is an antibody targeting JunD. Also known as JunD (Phospho-Ser255). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for JunD. It may not necessarily be applicable to this product.

NCBI GI #
102469037
NCBI GeneID
3727
NCBI Accession #
NP_005345.3
UniProt Primary Accession #
P17535
UniProt Secondary Accession #
Q53EK9
UniProt Related Accession #
P17535
GenBank Nucleotide #
NM_005354.5
NCBI Official Full Name
transcription factor jun-D isoform JunD-FL
NCBI Official Synonym Full Names
JunD proto-oncogene, AP-1 transcription factor subunit
NCBI Official Symbol
JUND
NCBI Official Synonym Symbols
AP-1
UniProt Protein Name
Transcription factor jun-D
Protein Family
Transcription factor
UniProt Gene Name
JUND
NCBI Protein Information
transcription factor jun-D

NCBI Summary for JunD

The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013]
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UniProt Comments for JunD

JunD: Transcription factor binding AP-1 sites. Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation. Belongs to the bZIP family. Jun subfamily.

Protein type: Motility/polarity/chemotaxis; Transcription factor

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: chromatin; nuclear chromatin; nucleus; transcription factor complex

Molecular Function: enzyme binding; protein binding; transcription coactivator activity; transcription factor binding

Biological Process: cellular response to hormone stimulus; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to cytokine stimulus; response to drug; response to lipopolysaccharide; response to mechanical stimulus; response to radiation
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Research Articles on JunD

1. CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-JunD antibody

 Reference Product  PubMed Publications
 FOS antibody  >488 publications with JunD and FOS
 FOSB antibody  >167 publications with JunD and FOSB
 MEN1 antibody  >44 publications with JunD and MEN1
 FOSL2 antibody  >38 publications with JunD and FOSL2
 SMAD3 antibody  >18 publications with JunD and SMAD3
 NFE2L2 antibody  >12 publications with JunD and NFE2L2
 MAPK3 antibody  >12 publications with JunD and MAPK3
 MAPK8 antibody  >11 publications with JunD and MAPK8
 MAPK1 antibody  >11 publications with JunD and MAPK1
 SMAD4 antibody  >9 publications with JunD and SMAD4

Pathways associated with anti-JunD antibody

 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Oncostatin M Signaling Pathway antibodies  Oncostatin M Signaling Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram

Diseases associated with anti-JunD antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >250 publications with JunD and Neoplasms
 Cell Transformation, Neoplastic Antibodies  >48 publications with JunD and Cell Transformation, Neoplastic
 Necrosis Antibodies  >44 publications with JunD and Necrosis
 Inflammation Antibodies  >35 publications with JunD and Inflammation
 Nervous System Diseases Antibodies  >32 publications with JunD and Nervous System Diseases
 Liver Diseases Antibodies  >29 publications with JunD and Liver Diseases
 Disease Models, Animal Antibodies  >24 publications with JunD and Disease Models, Animal
 Fibrosis Antibodies  >21 publications with JunD and Fibrosis
 Drug Toxicity Antibodies  >21 publications with JunD and Drug Toxicity
 Cardiovascular Diseases Antibodies  >21 publications with JunD and Cardiovascular Diseases

Organs/Tissues associated with anti-JunD antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >111 publications with JunD and Blood
 Brain Antibodies  >101 publications with JunD and Brain
 Bone Antibodies  >66 publications with JunD and Bone
 Liver Antibodies  >53 publications with JunD and Liver
 Muscle Antibodies  >42 publications with JunD and Muscle
 Lung Antibodies  >39 publications with JunD and Lung
 Skin Antibodies  >35 publications with JunD and Skin
 Vascular Antibodies  >29 publications with JunD and Vascular
 Kidney Antibodies  >23 publications with JunD and Kidney
 Embryonic Tissue Antibodies  >20 publications with JunD and Embryonic Tissue
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