Il-1racp (Ct) Antibody – Rabbit

Cellular responses induced by the proinflammatory cytokine IL-1 require two subunits of the IL-1 receptor, IL-1 receptor 1 (IL-1R1) and IL-1 receptor accessory protein (IL-1RacP). IL- 1RacP forms a complex with IL-1R1 in response to IL-1 treatment. IL-1 receptor-associated kinase (IRAK) mediates activation of NF- kappa B inducing kinase (NIK) and NF- kappa B and associates with the IL-1Rcomplex through IL- 1RacP. IL-1 activation of stressactivated protein kinase andof acid sphingomyelinase also requires IL- 1RacP. Like IL-1R1, the IL-1RacP subunit is essential for IL-1 mediated cellular responses. IL-1RacP is expressed in a variety of tissues.

Small volumes of anti-IL-1RAcP (CT) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS194107 is an antibody targeting IL-1RAcP (CT). Host: Rabbit.