TACE Antibody – Rabbit

Tumor necrosis factor alpha (TNF alpha ) is a proinflammatory cytokine and contributes to a variety of inflammatory reactions and to programmed cell death. TNF alpha is synthesized as a 26 kD type II membranebound precursor that is cleaved by a convertase to generate secreted 17 kD mature TNF alpha . TNF alpha converting enzyme (TACE) was recently identified, and human and mouse TACE cDNAs have been cloned. TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGF alpha , L-selectin, and alphacleavage of amyloid protein precursor (APP). TACE mRNA is expressed in a variety of human and mouse tissues.

Small volumes of anti-TACE (CT) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS194146 is an antibody targeting TACE (CT). Also known as Anti-TACE/ADAM17 Antibody. Host: Rabbit.