Human rHuKGF-2 Active Protein – Cat# MBS191483

Keratinocyte Growth Factor-2 (rHuKGF-2) Human Active Protein

Name: rHuKGF-2 Active Protein; Keratinocyte Growth Factor-2; Human; MyBioSource
Brand: MyBioSource
SKU: MBS191483
Price: 265 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS191483

Recombinant Human KGF-2 produced in E Coli is a single, non-glycosylated, polypeptide chain containing 170 amino acids with a molecular mass of 19,300 daltons. This product has full biological activity. More details

$265 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Keratinocyte Growth Factor-2 (rHuKGF-2), Active Protein

Full Product Name

Recombinant Human Keratinocyte Growth Factor-2

Product Gene Name

rHuKGF-2 active protein

Product Synonym Names

Human Keratinocyte Growth Factor-2 (rHuKGF-2)

Host

E Coli

Form/Format

Sterile filtered, lyophilized.

Purity/Purification

Greater than 97% by RP-HPLC, anion-exchange chromatography; reducing and non-reducing SDS-PAGE, silver stain.

Preparation and Storage

Lyophilized product is stable at room temperature for 3 weeks.
Store lyophilized product desiccated at-20 degree C.
Upon reconstitution, store at 4 degree C for 2-7 days or aliquot and store at-20 degree C.
For long-term storage add either HSA or BSA to 0.1%.
Avoid repeated freeze-thaw cycles.

Molecular Weight

23,436 Da

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Fully biologically active compared to reference standards. Specific Activity is 2 x106 Units/mg.

Endotoxin

<0.1 ng/ug

Stabilizers

None

Preservatives

None

Protein Content

Determined spectrophotometrically at 280nm (extinction coefficient 1.79) and by RPHPLC analysis against a calibrated standard.

Dimers/Aggregates

<1% by SDS-PAGE

Reconstitution

Reconstitute the lyophilized product in sterile water not less than 100 ug/ml. Dialyzed against 5mM sodium phosphate pH 7.4/80 mM NaCl prior to lyophilization.

Other Notes

Small volumes of rHuKGF-2 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for rHuKGF-2 purchase

MBS191483 is an active protein targeting rHuKGF-2. Also known as Recombinant Human Keratinocyte Growth Factor-2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for rHuKGF-2. It may not necessarily be applicable to this product.

NCBI GI #

2231295

NCBI GeneID

2255

NCBI Accession #

AAB61991.1

UniProt Secondary Accession #

Q6FHR3; Q6FHT6; Q96P59; C7FDY0

UniProt Related Accession #

O15520

NCBI Official Full Name

keratinocyte growth factor 2

NCBI Official Synonym Full Names

fibroblast growth factor 10

NCBI Official Symbol

FGF10

UniProt Protein Name

Fibroblast growth factor 10

UniProt Synonym Protein Names

Keratinocyte growth factor 2

UniProt Gene Name

FGF10

UniProt Synonym Gene Names

FGF-10

NCBI Protein Information

fibroblast growth factor 10

NCBI Summary for rHuKGF-2

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq, Jul 2008]

UniProt Comments for rHuKGF-2

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing.

Research Articles on rHuKGF-2

1. We report the ophthalmological and genetic study of a 19-year-old woman and her relatives suffering from this syndrome. A new probably pathogenic variant is described in the FGF10 gene.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with rHuKGF-2 active protein

Reference Product	PubMed Publications
FGFR2 active protein	>132 publications with rHuKGF-2 and FGFR2
POMC active protein	>2 publications with rHuKGF-2 and POMC

Pathways associated with rHuKGF-2 active protein

Products by Pathway	Pathway Diagram
Downstream Signaling Of Activated FGFR Pathway antibodies	Downstream Signaling Of Activated FGFR Pathway Diagram
FGFR Ligand Binding And Activation Pathway antibodies	FGFR Ligand Binding And Activation Pathway Diagram
FGFR1 Ligand Binding And Activation Pathway antibodies	FGFR1 Ligand Binding And Activation Pathway Diagram
FGFR1b Ligand Binding And Activation Pathway antibodies	FGFR1b Ligand Binding And Activation Pathway Diagram
FGFR2 Ligand Binding And Activation Pathway antibodies	FGFR2 Ligand Binding And Activation Pathway Diagram
FGFR2b Ligand Binding And Activation Pathway antibodies	FGFR2b Ligand Binding And Activation Pathway Diagram
FRS2-mediated Cascade Pathway antibodies	FRS2-mediated Cascade Pathway Diagram
Heart Development Pathway antibodies	Heart Development Pathway Diagram
IRS-mediated Signalling Pathway antibodies	IRS-mediated Signalling Pathway Diagram
IRS-related Events Pathway antibodies	IRS-related Events Pathway Diagram

Diseases associated with rHuKGF-2 active protein

Disease Name	Pubmed Publications
Congenital Abnormalities Antibodies	>83 publications with rHuKGF-2 and Congenital Abnormalities
Neoplasms Antibodies	>32 publications with rHuKGF-2 and Neoplasms
Craniofacial Abnormalities Antibodies	>26 publications with rHuKGF-2 and Craniofacial Abnormalities
Cleft Palate Antibodies	>19 publications with rHuKGF-2 and Cleft Palate
Limb Deformities, Congenital Antibodies	>18 publications with rHuKGF-2 and Limb Deformities, Congenital
Genital Diseases, Male Antibodies	>16 publications with rHuKGF-2 and Genital Diseases, Male
Carcinoma Antibodies	>15 publications with rHuKGF-2 and Carcinoma
Lung Diseases Antibodies	>14 publications with rHuKGF-2 and Lung Diseases
Jaw Abnormalities Antibodies	>14 publications with rHuKGF-2 and Jaw Abnormalities
Inflammation Antibodies	>13 publications with rHuKGF-2 and Inflammation

Organs/Tissues associated with rHuKGF-2 active protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>38 publications with rHuKGF-2 and Muscle
Brain Antibodies	>33 publications with rHuKGF-2 and Brain
Intestine Antibodies	>27 publications with rHuKGF-2 and Intestine
Kidney Antibodies	>20 publications with rHuKGF-2 and Kidney
Trachea Antibodies	>15 publications with rHuKGF-2 and Trachea
Uterus Antibodies	>7 publications with rHuKGF-2 and Uterus
Mixed Antibodies	>4 publications with rHuKGF-2 and Mixed