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Groes (Hsp10) (GroES) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS197042

Hsp10 is a molecular chaperone that plays a role in protein folding under normal and stress conditions. It binds to Hsp60 in the presence of ATP causing a change in Hsp60 conformation and thus enclosing a protein substrate within this complex. ATP hydrolysis… More details

$265 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GroES (Hsp10), Recombinant Protein
Full Product Name
Recombinant Human GroES (Hsp10)
Product Gene Name
Sequence
MAGQAFRKFL PLFDRVLVER SAAETVTKGG IMLPEKSQGK VLQATVVAVG SGSKGKGGEI QPVSVKVGDK VLLPEYGGTK VVLDDKDYFL FRDGDILGKY VD
Host
E Coli
Form/Format
Sterile-filtered colorless solution contains 20mM Tris buffer, pH 8.0, and 50mM NaCl. Purified by proprietary chromatographic techniques.
Purity/Purification
Greater than 98% as determined by SDS-PAGE and RP-HPLC.
Specificity
Human GroES (Hsp10)
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store at or below -20 degree C for longer periods of time. For long term storage, addition of a carrier protein (0.1% HSA or BSA) is recommended.
Molecular Weight
10,932 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (198364721..198368187). Location: 2q33.1
OMIM
600141
3D Structure
ModBase 3D Structure for P61604

Other Notes

Small volumes of GroES recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GroES purchase

MBS197042 is a recombinant protein targeting GroES. Also known as Recombinant Human GroES (Hsp10). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GroES. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
10 kDa heat shock protein, mitochondrial
NCBI Official Synonym Full Names
heat shock 10kDa protein 1 (chaperonin 10)
NCBI Official Symbol
HSPE1
NCBI Official Synonym Symbols
EPF; CPN10; GROES; HSP10
UniProt Protein Name
10 kDa heat shock protein, mitochondrial
UniProt Synonym Protein Names
10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor
UniProt Gene Name
HSPE1
UniProt Entry Name
CH10_HUMAN
NCBI Protein Information
10 kDa heat shock protein, mitochondrial; chaperonin 10; 10 kDa chaperonin; OTTHUMP00000163630; OTTHUMP00000205751; OTTHUMP00000205752; early-pregnancy factor; heat shock 10kD protein 1 (chaperonin 10)

NCBI Summary for GroES

This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.
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UniProt Comments for GroES

HSPE1: Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. Belongs to the GroES chaperonin family.

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 2q33.1

Cellular Component: membrane; mitochondrion; mitochondrial matrix

Molecular Function: protein binding; chaperone binding; unfolded protein binding; ATP binding

Biological Process: caspase activation; osteoblast differentiation; protein folding; response to unfolded protein
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GroES recombinant protein

 Reference Product  PubMed Publications
 HSPD1 recombinant protein  >8 publications with GroES and HSPD1
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