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Heat Shock 70kDa Binding Protein 1 (HSPBP1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2001478
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MBS2001478 is an antibody targeting HSPBP1. Also known as Polyclonal Antibody to Heat Shock 70kDa Binding Protein 1 (HSPBP1). Reactive in Rat, Human, Mouse. Host: Rabbit. More details

$220 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Heat Shock 70kDa Binding Protein 1 (HSPBP1), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Heat Shock 70kDa Binding Protein 1 (HSPBP1)
Product Gene Name
Immunogen Sequence
Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG SEF-SCD TVRVKALFAI SCLVREQEAG LLQFLRLDGF SVLMRAMQQQ VQKLKVKSAF LLQNLLVGHP EHKGTLCSMG MVQQLVALVR TEHSPFHEHV LGALCSLVTD FPQGVRECRE PELGLEELLR HRCQLLQQHE EYQEELEFCE KLLQTCFSSP TD
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat, Human, Mouse
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against HSPBP1. It has been selected for its ability to recognize HSPBP1 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: HSPBP1 (MBS2001478)
Biotin Conjugated Antibody: HSPBP1 (MBS2003900)
Matching Pairs
Unconjugated Antibody: HSPBP1 (MBS2001478)
Immunogen: HSPBP1 (MBS2009524)
Molecular Weight
39,191 Da
3D Structure
ModBase 3D Structure for Q6IMX7
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant HSPBP1 (Ser198~Asp352) expressed in E.coli.
Cross Reactivity
Rat
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2071688
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-HSPBP1 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-HSPBP1 antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-HSPBP1 antibody

Western Blot: Sample: Rat Serum.
Rabbit Anti-HSPBP1 Polyclonal Antibody – Cat# MBS2001478

Western Blot (WB) of anti-HSPBP1 antibody

Western Blot: Sample: Recombinant HSPBP1, Rat.
Rabbit Anti-HSPBP1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS2001478

Immunohistochemistry (IHC) of anti-HSPBP1 antibody

DAB staining on IHC-P; Samples: Rat Lung Tissue.
Rabbit Anti-HSPBP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2001478

Immunohistochemistry (IHC) of anti-HSPBP1 antibody

DAB staining on IHC-P; Samples: Rat Spleen Tissue
Rabbit Anti-HSPBP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2001478

Immunohistochemistry (IHC) of anti-HSPBP1 antibody

DAB staining on IHC-P; Samples: Rat Liver Tissue
Rabbit Anti-HSPBP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2001478

Other Notes

Small volumes of anti-HSPBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HSPBP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
hsp70-binding protein 1
NCBI Official Synonym Full Names
HSPA (Hsp70) binding protein 1
NCBI Official Symbol
Hspbp1
UniProt Protein Name
Hsp70-binding protein 1
UniProt Synonym Protein Names
Heat shock protein-binding protein 1; Hsp70-interacting protein 1
Protein Family
UniProt Gene Name
Hspbp1
UniProt Synonym Gene Names
Hspbp; HspBP1
NCBI Protein Information
hsp70-binding protein 1

NCBI Summary for HSPBP1

inhibits chaperone activity by preventing ATP binding [RGD, Feb 2006]

UniProt Comments for HSPBP1

HSPBP1: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of target proteins (By similarity)

Chromosomal Location of Human Ortholog: 1q12

Molecular Function: enzyme inhibitor activity

Biological Process: negative regulation of catalytic activity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein ubiquitination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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