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Alpha-1-Acid Glycoprotein (a1AGP) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2001513
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2001513 is an antibody targeting a1AGP. Also known as Polyclonal Antibody to Alpha-1-Acid Glycoprotein (a1AGP). Reactive in Human, Rat. Host: Rabbit. More details

$205 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Alpha-1-Acid Glycoprotein (a1AGP), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Alpha-1-Acid Glycoprotein (a1AGP)
Product Gene Name
anti-a1AGP antibody
Product Synonym Names
GLG1, CFR-1, ESL-1, MG-160, MG160, golgi glycoprotein 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
1mg/ml (lot specific)
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: a1AGP (MBS2001513)
Biotin Conjugated Antibody: a1AGP (MBS2001433)
Matching Pairs
Unconjugated Antibody: a1AGP (MBS2001513)
Immunogen: a1AGP (MBS2011236)
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Molecular Weight
Calculated: 134kDa/135/kDa/137kDa
Observed: 135kDa
OMIM
X02544 mRNA
3D Structure
ModBase 3D Structure for P02763
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Organism Species
Homo sapiens (Human)
Source
Polyclonal antibody preparation
Traits
Liquid
Immunogen
Recombinant a1AGP (Gln19~Ser201) expressed in E.coli
Cross Reactivity
Human
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-a1AGP antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-a1AGP antibody
Western blotting: 0.5-2 ug/mL;1:500-2000
Immunohistochemistry: 5-20 ug/mL;1:50-200
Immunocytochemistry: 5-20 ug/mL;1:50-200

Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-a1AGP antibody

Western Blot: Sample: Human Serum; Primary Ab: 2ug/ml Rabbit Anti-Human a1AGP Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Rabbit Anti-a1AGP Polyclonal Antibody – Cat# MBS2001513

Western Blot (WB) of anti-a1AGP antibody

Western Blot: Sample: Human Plasma; Primary Ab: 1ug/ml Rabbit Anti-Human a1AGP Antibody Second Ab:
Rabbit Anti-a1AGP Polyclonal Antibody, Western Blot (WB) – Cat# MBS2001513

Western Blot (WB) of anti-a1AGP antibody

Western Blot; Sample: Rat Cerebrum lysate; Primary Ab: 1ug/ml Rabbit Anti-Human a1AGP Antibody; Second Ab: 0.2 ug/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (MBS2086047)
Rabbit Anti-a1AGP Polyclonal Antibody, Western Blot (WB) – Cat# MBS2001513

Immunohistochemistry (IHC) of anti-a1AGP antibody

DAB staining on fromalin fixed paraffin-embedded Liver tissue)
Rabbit Anti-a1AGP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2001513

Other Notes

Small volumes of anti-a1AGP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for a1AGP. It may not necessarily be applicable to this product.

NCBI GI #
167857790
NCBI GeneID
5004
NCBI Accession #
NP_000598.2
UniProt Primary Accession #
P02763
UniProt Secondary Accession #
Q5T539; Q5U067; Q8TC16; B7ZKQ5
UniProt Related Accession #
P02763; AAB33887
GenBank Nucleotide #
NM_000607.2
NCBI Official Full Name
alpha-1-acid glycoprotein 1
NCBI Official Synonym Full Names
orosomucoid 1
NCBI Official Symbol
ORM1
NCBI Official Synonym Symbols
ORM; AGP1; AGP-A; HEL-S-153w
UniProt Protein Name
Alpha-1-acid glycoprotein 1
UniProt Synonym Protein Names
Orosomucoid-1; OMD 1
UniProt Gene Name
ORM1
UniProt Synonym Gene Names
AGP1; AGP 1; OMD 1
NCBI Protein Information
alpha-1-acid glycoprotein 1

NCBI Summary for a1AGP

This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]
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UniProt Comments for a1AGP

ORM1: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Belongs to the calycin superfamily. Lipocalin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q32

Cellular Component: extracellular matrix; extracellular region; extracellular space

Molecular Function: protein binding

Biological Process: acute-phase response; inflammatory response; negative regulation of interleukin-6 production; negative regulation of tumor necrosis factor production; neutrophil degranulation; platelet degranulation; positive regulation of interleukin-1 beta secretion; positive regulation of interleukin-1 secretion; regulation of immune system process
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Research Articles on a1AGP

1. Data suggest that serum haptoglobin, fetuin-A, platelet factor-4, hs-CRP (high sensitive-C-reactive protein), SAP (serum amyloid P), AGP (alpha1-acid glycoprotein) levels of adolescents with metabolic syndrome are significantly higher than those of controls subjects.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-a1AGP antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >16 publications with a1AGP and Inflammation
 Neoplasms Antibodies  >7 publications with a1AGP and Neoplasms
 Breast Neoplasms Antibodies  >4 publications with a1AGP and Breast Neoplasms
 Nervous System Diseases Antibodies  >3 publications with a1AGP and Nervous System Diseases
 Drug Toxicity Antibodies  >3 publications with a1AGP and Drug Toxicity
 Death Antibodies  >3 publications with a1AGP and Death
 Lung Neoplasms Antibodies  >2 publications with a1AGP and Lung Neoplasms
 Heart Diseases Antibodies  >2 publications with a1AGP and Heart Diseases
 Pain Antibodies  >2 publications with a1AGP and Pain
 Necrosis Antibodies  >2 publications with a1AGP and Necrosis

Organs/Tissues associated with anti-a1AGP antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >46 publications with a1AGP and Blood
 Liver Antibodies  >9 publications with a1AGP and Liver
 Lung Antibodies  >6 publications with a1AGP and Lung
 Heart Antibodies  >4 publications with a1AGP and Heart
 Lymph Node Antibodies  >1 publications with a1AGP and Lymph Node
 Connective Tissue Antibodies  >1 publications with a1AGP and Connective Tissue
 Muscle Antibodies  >1 publications with a1AGP and Muscle
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