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Oxytocin Receptor (OXTR) Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2002159
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MBS2002159 is an antibody targeting OXTR. Also known as Polyclonal Antibody to Oxytocin Receptor (OXTR). Host: Rabbit. More details

$215 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Oxytocin Receptor (OXTR), Antibody
Full Product Name
Polyclonal Antibody to Oxytocin Receptor (OXTR)
Product Gene Name
anti-OXTR antibody
Host
Rabbit
Form/Format
Liquid; Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
0.5mg/mL (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: OXTR (MBS2002159)
Immunogen: OXTR (MBS2009192)
Matching Pairs
Unconjugated Antibody: OXTR (MBS2002159)
FITC Conjugated Antibody: OXTR (MBS2014259)
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OMIM
X64878 mRNA
3D Structure
ModBase 3D Structure for P30559
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Cross Reactivity
Mouse, Rat
Immunogen
Recombinant OXTR (Arg272~Ser377) expressed in E.coli
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-OXTR antibody
Western Blot (WB)
Application Notes for anti-OXTR antibody
Western blotting: 0.01-2ug/mL

Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-OXTR antibody

Western Blot: Sample: Recombinant OXTR, Human.
Rabbit Anti-OXTR Antibody – Cat# MBS2002159

Other Notes

Small volumes of anti-OXTR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for OXTR. It may not necessarily be applicable to this product.

NCBI GI #
32307152
NCBI GeneID
5021
NCBI Accession #
NP_000907.2
UniProt Primary Accession #
P30559
UniProt Secondary Accession #
Q15071
UniProt Related Accession #
P30559
GenBank Nucleotide #
NM_000916.3
NCBI Official Full Name
oxytocin receptor
NCBI Official Synonym Full Names
oxytocin receptor
NCBI Official Symbol
OXTR
NCBI Official Synonym Symbols
OT-R
UniProt Protein Name
Oxytocin receptor
Protein Family
Oxytocin receptor
UniProt Gene Name
OXTR
UniProt Synonym Gene Names
OT-R
NCBI Protein Information
oxytocin receptor

NCBI Summary for OXTR

The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]
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UniProt Comments for OXTR

OXTR: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 3p25.3

Cellular Component: apical plasma membrane; cell-cell adherens junction; integral component of plasma membrane; intracellular; microvillus; plasma membrane

Molecular Function: oxytocin receptor activity; peptide binding; peptide hormone binding; vasopressin receptor activity

Biological Process: cell surface receptor signaling pathway; cellular response to hormone stimulus; eating behavior; elevation of cytosolic calcium ion concentration; female pregnancy; G-protein coupled receptor signaling pathway; gut development; heart development; lactation; maternal behavior; maternal process involved in parturition; memory; muscle contraction; positive regulation of blood pressure; positive regulation of synaptic transmission, GABAergic; positive regulation of synaptic transmission, glutamatergic; positive regulation of synaptogenesis; positive regulation of vasoconstriction; regulation of systemic arterial blood pressure by vasopressin; response to amphetamine; response to anoxia; response to cocaine; response to cytokine; response to drug; response to estradiol; response to peptide hormone; response to progesterone; sleep; social behavior; sperm ejaculation; suckling behavior; telencephalon development
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Research Articles on OXTR

1. Individuals homozygous for the G allele of OXTR rs1042778 experience gains in daily positive emotions from loving-kindness training, whereas individuals with the T allele do not experience gains in positive emotions with either training.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OXTR antibody

 Reference Product  PubMed Publications
 OXT antibody  >62 publications with OXTR and OXT

Pathways associated with anti-OXTR antibody

 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram

Diseases associated with anti-OXTR antibody

 Disease Name  Pubmed Publications
 Child Development Disorders, Pervasive Antibodies  >33 publications with OXTR and Child Development Disorders, Pervasive
 Autistic Disorder Antibodies  >30 publications with OXTR and Autistic Disorder
 Cognition Disorders Antibodies  >17 publications with OXTR and Cognition Disorders
 Schizophrenia Antibodies  >10 publications with OXTR and Schizophrenia
 Inflammation Antibodies  >8 publications with OXTR and Inflammation
 Depressive Disorder Antibodies  >7 publications with OXTR and Depressive Disorder
 Premature Birth Antibodies  >6 publications with OXTR and Premature Birth
 Pancreatic Neoplasms Antibodies  >4 publications with OXTR and Pancreatic Neoplasms
 Disease Models, Animal Antibodies  >4 publications with OXTR and Disease Models, Animal
 Pain Antibodies  >4 publications with OXTR and Pain

Organs/Tissues associated with anti-OXTR antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >104 publications with OXTR and Brain
 Uterus Antibodies  >28 publications with OXTR and Uterus
 Connective Tissue Antibodies  >6 publications with OXTR and Connective Tissue
 Heart Antibodies  >6 publications with OXTR and Heart
 Embryonic Tissue Antibodies  >5 publications with OXTR and Embryonic Tissue
 Ovary Antibodies  >4 publications with OXTR and Ovary
 Liver Antibodies  >3 publications with OXTR and Liver
 Lung Antibodies  >2 publications with OXTR and Lung
 Kidney Antibodies  >2 publications with OXTR and Kidney
 Skin Antibodies  >2 publications with OXTR and Skin
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