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Galectin 9 (GAL9) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2002353
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MBS2002353 is an antibody targeting GAL9. Also known as Polyclonal Antibody to Galectin 9 (GAL9). Reactive in Mouse. Host: Rabbit. More details

$205 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Galectin 9 (GAL9), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Galectin 9 (GAL9)
Product Gene Name
anti-GAL9 antibody
Immunogen Sequence
Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG SEF- FYTPIP NGLYPSKSIM ISGNVLPDAT RFHINLRCGG DIAFHLNPRF NENAVVRNTQ INNSWGQEER SLLGRMPFSR GQSFSVWIIC EGHCFKVAVN GQHMCEYYHR LKNLQDINTL EVAGDIQLTH VQT
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against GAL9. It has been selected for its ability to recognize GAL9 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: GAL9 (MBS2002353)
Immunogen: GAL9 (MBS2011772)
Matching Pairs
Unconjugated Antibody: GAL9 (MBS2002353)
APC-CY7 Conjugated Antibody: GAL9 (MBS2040920)
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Molecular Weight
35,164 Da
3D Structure
ModBase 3D Structure for O08573
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant GAL9 (Phe225~Thr353) expressed in E.coli.
Cross Reactivity
Mouse
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2040924
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-GAL9 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-GAL9 antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-GAL9 antibody

Western Blot: Sample: Recombinant GAL9, Mouse.
Rabbit Anti-GAL9 Polyclonal Antibody – Cat# MBS2002353

Immunohistochemistry (IHC) of anti-GAL9 antibody

DAB staining on IHC-P; Samples: Mouse Kidney Tissue
Rabbit Anti-GAL9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2002353

Immunohistochemistry (IHC) of anti-GAL9 antibody

DAB staining on IHC-P; Samples: Mouse Liver Tissue.
Rabbit Anti-GAL9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2002353

Immunohistochemistry (IHC) of anti-GAL9 antibody

DAB staining on IHC-P; Samples: Mouse Kidney Tissue.
Rabbit Anti-GAL9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2002353

Immunohistochemistry (IHC) of anti-GAL9 antibody

DAB staining on IHC-P; Samples: Mouse Lymph Node Tissue.
Rabbit Anti-GAL9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2002353

Other Notes

Small volumes of anti-GAL9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GAL9. It may not necessarily be applicable to this product.

NCBI GI #
226531139
NCBI GeneID
16859
NCBI Accession #
NP_001152773.1
UniProt Primary Accession #
O08573
UniProt Secondary Accession #
O08572; Q3UKE5; Q99L83
UniProt Related Accession #
O08573
GenBank Nucleotide #
NM_001159301.1
NCBI Official Full Name
galectin-9 isoform 2
NCBI Official Synonym Full Names
lectin, galactose binding, soluble 9
NCBI Official Symbol
Lgals9
NCBI Official Synonym Symbols
gal-9; Lgals5; LGALS35; AA407335; AI194909; AI265545; galectin-9
UniProt Protein Name
Galectin-9
Protein Family
Gallinacin
UniProt Gene Name
Lgals9
UniProt Synonym Gene Names
Gal-9
NCBI Protein Information
galectin-9

UniProt Comments for GAL9

galectin-9: Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 11|11 B5

Cellular Component: cytoplasm; cytosol; extracellular region; intracellular; nucleus

Molecular Function: carbohydrate binding; enzyme binding; galactoside binding; protein binding; protein serine/threonine kinase activator activity; receptor binding

Biological Process: chemotaxis; female pregnancy; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; immune system process; maintenance of protein location; negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of gene expression; negative regulation of inflammatory response; negative regulation of interferon-gamma production; negative regulation of interferon-gamma secretion; negative regulation of natural killer cell activation; negative regulation of natural killer cell degranulation; positive regulation of chemokine production; positive regulation of cytokine production; positive regulation of defense response to bacterium; positive regulation of gene expression; positive regulation of innate immune response; positive regulation of interleukin-1 production; positive regulation of interleukin-10 secretion; positive regulation of interleukin-6 secretion; positive regulation of macrophage activation; positive regulation of oxidoreductase activity; positive regulation of pathway-restricted SMAD protein phosphorylation; positive regulation of regulatory T cell differentiation; positive regulation of T cell migration; positive regulation of transcription regulatory region DNA binding; positive regulation of tumor necrosis factor production; regulation of natural killer cell differentiation; regulation of T cell chemotaxis; regulation of T cell differentiation in the thymus; regulation of T-helper 17 type immune response; response to lipopolysaccharide; toll-like receptor 3 signaling pathway
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Research Articles on GAL9

1. in a model of experimental autoimmune encephalomyelitis, we show that an agonist of DR3 suppressed disease, correlating with expansion of CD4+Foxp3+ Tregs, and this protective effect was lost in Galectin-9-/- mice

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-GAL9 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >37 publications with GAL9 and Inflammation
 Disease Models, Animal Antibodies  >12 publications with GAL9 and Disease Models, Animal
 Liver Diseases Antibodies  >12 publications with GAL9 and Liver Diseases
 Necrosis Antibodies  >10 publications with GAL9 and Necrosis
 Hepatitis Antibodies  >10 publications with GAL9 and Hepatitis
 Liver Neoplasms Antibodies  >6 publications with GAL9 and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >6 publications with GAL9 and Neoplasm Metastasis
 Kidney Diseases Antibodies  >4 publications with GAL9 and Kidney Diseases
 Carcinoma, Hepatocellular Antibodies  >4 publications with GAL9 and Carcinoma, Hepatocellular
 Breast Neoplasms Antibodies  >4 publications with GAL9 and Breast Neoplasms

Organs/Tissues associated with anti-GAL9 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >109 publications with GAL9 and Blood
 Liver Antibodies  >14 publications with GAL9 and Liver
 Kidney Antibodies  >14 publications with GAL9 and Kidney
 Lung Antibodies  >12 publications with GAL9 and Lung
 Lymph Node Antibodies  >8 publications with GAL9 and Lymph Node
 Embryonic Tissue Antibodies  >8 publications with GAL9 and Embryonic Tissue
 Intestine Antibodies  >7 publications with GAL9 and Intestine
 Brain Antibodies  >5 publications with GAL9 and Brain
 Muscle Antibodies  >4 publications with GAL9 and Muscle
 Thymus Antibodies  >3 publications with GAL9 and Thymus
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