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Ephrin A4 (EFNA4) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2002398
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MBS2002398 is an antibody targeting EFNA4. Also known as Polyclonal Antibody to Ephrin A4 (EFNA4). Reactive in Mouse. Host: Rabbit. More details

$215 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ephrin A4 (EFNA4), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Ephrin A4 (EFNA4)
Product Gene Name
anti-EFNA4 antibody
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-MRL LPLLRTV LWAALLGSRL PGCSSLRHPI YWNSSNPRLL RGDAVVELGF NDYLDIFCPH YESPGPPEGP ETFALYMVDW SGYEACTAEG ANAFQRWNCS MPFAPFSPVR FSEKIQRYTP FPLGFEFLPG ETYYYISVPT PESPGRCLRL QVSVCCKESG SSHESAHPVG SPGESGTSGW RGGHAPSPLC LLLLLLLPIL RLLRVL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against EFNA4. It has been selected for its ability to recognize EFNA4 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: EFNA4 (MBS2002398)
Immunogen: EFNA4 (MBS2009096)
Matching Pairs
Unconjugated Antibody: EFNA4 (MBS2002398)
APC-CY7 Conjugated Antibody: EFNA4 (MBS2073922)
Show more
Molecular Weight
22,861 Da
3D Structure
ModBase 3D Structure for O08542
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant EFNA4 (Met1~Leu206) expressed in E.coli.
Cross Reactivity
Mouse
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2073924
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-EFNA4 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-EFNA4 antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-EFNA4 antibody

Western Blot: Sample: Lane1: Mouse Spleen Tissue; Lane2: Mouse Ovary Tissue; Lane3: Mouse Thymus Tissue.
Rabbit Anti-EFNA4 Polyclonal Antibody – Cat# MBS2002398

Western Blot (WB) of anti-EFNA4 antibody

Western Blot: Sample: Recombinant EFNA4, Mouse.
Rabbit Anti-EFNA4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS2002398

Immunohistochemistry (IHC) of anti-EFNA4 antibody

DAB staining on IHC-P; Samples: Mouse Liver Tissue
Rabbit Anti-EFNA4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2002398

Immunohistochemistry (IHC) of anti-EFNA4 antibody

DAB staining on IHC-P; Samples: Mouse Kidney Tissue.
Rabbit Anti-EFNA4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2002398

Other Notes

Small volumes of anti-EFNA4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EFNA4. It may not necessarily be applicable to this product.

NCBI GI #
110835739
NCBI GeneID
13639
NCBI Accession #
NP_031936.2
UniProt Primary Accession #
O08542
UniProt Secondary Accession #
O55218
UniProt Related Accession #
O08542
GenBank Nucleotide #
NM_007910.2
NCBI Official Full Name
ephrin-A4
NCBI Official Synonym Full Names
ephrin A4
NCBI Official Symbol
Efna4
NCBI Official Synonym Symbols
Epl4; EFL-4; LERK-4
UniProt Protein Name
Ephrin-A4
UniProt Synonym Protein Names
EPH-related receptor tyrosine kinase ligand 4; LERK-4
Protein Family
Ephrin
UniProt Gene Name
Efna4
UniProt Synonym Gene Names
Epl4; Eplg4; Lerk4; LERK-4
NCBI Protein Information
ephrin-A4

UniProt Comments for EFNA4

EFNA4: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils. Belongs to the ephrin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ligand, receptor tyrosine kinase; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 3 F1|3 39.07 cM

Cellular Component: membrane; plasma membrane

Molecular Function: ephrin receptor binding

Biological Process: axon guidance; bone remodeling; ephrin receptor signaling pathway; osteoclast differentiation
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Research Articles on EFNA4

1. In a model of temporal lobe epilepsy, Ephrin-A4 and Ephrin-A5 increase in the hippocampus in a spatiotemporal course.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-EFNA4 antibody

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Ras Signaling Pathway antibodies  Ras Signaling Pathway Diagram

Diseases associated with anti-EFNA4 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with EFNA4 and Neoplasms
 Immune System Diseases Antibodies  >3 publications with EFNA4 and Immune System Diseases
 Bone Diseases Antibodies  >2 publications with EFNA4 and Bone Diseases
 Colonic Neoplasms Antibodies  >1 publications with EFNA4 and Colonic Neoplasms
 Nervous System Diseases Antibodies  >1 publications with EFNA4 and Nervous System Diseases
 Chromosome Aberrations Antibodies  >1 publications with EFNA4 and Chromosome Aberrations
 Necrosis Antibodies  >1 publications with EFNA4 and Necrosis

Organs/Tissues associated with anti-EFNA4 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with EFNA4 and Brain
 Intestine Antibodies  >1 publications with EFNA4 and Intestine
 Embryonic Tissue Antibodies  >1 publications with EFNA4 and Embryonic Tissue
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