• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Carnitine Palmitoyltransferase 1a, Liver (CPT1A) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2002410
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2002410 is an antibody targeting CPT1A. Also known as Polyclonal Antibody to Carnitine Palmitoyltransferase 1A, Liver (CPT1A). Reactive in Rat. Host: Rabbit. More details

$220 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Carnitine Palmitoyltransferase 1A, Liver (CPT1A), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Carnitine Palmitoyltransferase 1A, Liver (CPT1A)
Product Gene Name
anti-CPT1A antibody
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF -LALQLAHYK DMGKFCLTYE ASMTRLFREG RTETVRSCTM ESCNFVQAMM DPKSTAEQRL KLFKIACEKH QHLYRLAMTG AGIDRHLFCL YVVSKYLAVD SPFLKEVLSE PWRLSTSQTP QQQVELFDFE KNPDYVSCGG GFGPVADDGY GVSYIIVGEN FIHFHISSKF SSPETDSHRF GKHLRQAMMD IITLFGLTIN SKK
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against CPT1A. It has been selected for its ability to recognize CPT1A in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: CPT1A (MBS2002410)
Biotin Conjugated Antibody: CPT1A (MBS2006828)
Matching Pairs
Unconjugated Antibody: CPT1A (MBS2002410)
Immunogen: CPT1A (MBS2009652)
Show more
Molecular Weight
88,125 Da
3D Structure
ModBase 3D Structure for P32198
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant CPT1A (Leu572-Lys773) expressed in E.coli.
Cross Reactivity
Rat
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2076397
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CPT1A antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-CPT1A antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-CPT1A antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-CPT1A Polyclonal Antibody – Cat# MBS2002410

Immunohistochemistry (IHC) of anti-CPT1A antibody

DAB staining on fromalin fixed paraffin- embedded adrenal gland tissue)
Rabbit Anti-CPT1A Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2002410

Immunohistochemistry (IHC) of anti-CPT1A antibody

DAB staining on IHC-P; Samples: Rat Adrenal gland Tissue)
Rabbit Anti-CPT1A Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2002410

Other Notes

Small volumes of anti-CPT1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CPT1A. It may not necessarily be applicable to this product.

NCBI GI #
162287173
NCBI GeneID
25757
NCBI Accession #
NP_113747.2
UniProt Primary Accession #
P32198
UniProt Secondary Accession #
P97780; Q6IMZ4
UniProt Related Accession #
P32198
GenBank Nucleotide #
NM_031559.2
NCBI Official Full Name
carnitine O-palmitoyltransferase 1, liver isoform
NCBI Official Synonym Full Names
carnitine palmitoyltransferase 1A
NCBI Official Symbol
Cpt1a
NCBI Official Synonym Symbols
CPT-Ia
UniProt Protein Name
Carnitine O-palmitoyltransferase 1, liver isoform
UniProt Synonym Protein Names
Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1A
Protein Family
Carnitine O-palmitoyltransferase
UniProt Gene Name
Cpt1a
UniProt Synonym Gene Names
Cpt-1; Cpt1; CPT1-L; CPT I; CPTI-L
NCBI Protein Information
carnitine O-palmitoyltransferase 1, liver isoform

NCBI Summary for CPT1A

enzyme that catalyses the transfer of long chain fatty acids to carnitine for translocation across the mitochondrial inner membrane [RGD, Feb 2006]

UniProt Comments for CPT1A

CPT1A: Belongs to the carnitine/choline acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.3.1.21; Lipid Metabolism - fatty acid; Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transferase

Chromosomal Location of Human Ortholog: 1q42

Cellular Component: endoplasmic reticulum membrane; integral component of membrane; integral to mitochondrial outer membrane; intracellular membrane-bound organelle; membrane; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion

Molecular Function: carnitine O-palmitoyltransferase activity; identical protein binding; protein binding

Biological Process: carnitine metabolic process; eating behavior; epithelial cell differentiation; fatty acid beta-oxidation; glucose metabolic process; long-chain fatty acid metabolic process; positive regulation of fatty acid beta-oxidation; protein homooligomerization; regulation of fatty acid beta-oxidation; regulation of fatty acid oxidation; regulation of insulin secretion; response to drug; response to organic cyclic compound; transport; triacylglycerol metabolic process
Show more

Research Articles on CPT1A

1. Furthermore, given the already low abundance of Cpt1b in white adipose tissue, it is unlikely that decreases in its expression can quantitatively decrease whole body energy expenditure enough to contribute to an obese phenotype.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CPT1A antibody

 Reference Product  PubMed Publications
 Cpt2 antibody  >14 publications with CPT1A and Cpt2
 Ppargc1a antibody  >13 publications with CPT1A and Ppargc1a
 Ppara antibody  >12 publications with CPT1A and Ppara
 Acsl1 antibody  >11 publications with CPT1A and Acsl1
 Rxra antibody  >2 publications with CPT1A and Rxra
 Slc25a20 antibody  >1 publications with CPT1A and Slc25a20

Pathways associated with anti-CPT1A antibody

 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Beta Oxidation Meta Pathway antibodies  Beta Oxidation Meta Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram

Diseases associated with anti-CPT1A antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >138 publications with CPT1A and Fatty Liver
 Liver Diseases Antibodies  >64 publications with CPT1A and Liver Diseases
 Insulin Resistance Antibodies  >50 publications with CPT1A and Insulin Resistance
 Inflammation Antibodies  >31 publications with CPT1A and Inflammation
 Non-alcoholic Fatty Liver Disease Antibodies  >20 publications with CPT1A and Non-alcoholic Fatty Liver Disease
 Weight Gain Antibodies  >18 publications with CPT1A and Weight Gain
 Atherosclerosis Antibodies  >14 publications with CPT1A and Atherosclerosis
 Diabetes Mellitus Antibodies  >14 publications with CPT1A and Diabetes Mellitus
 Dyslipidemias Antibodies  >12 publications with CPT1A and Dyslipidemias
 Hepatitis Antibodies  >11 publications with CPT1A and Hepatitis

Organs/Tissues associated with anti-CPT1A antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >172 publications with CPT1A and Liver
 Brain Antibodies  >28 publications with CPT1A and Brain
 Connective Tissue Antibodies  >21 publications with CPT1A and Connective Tissue
 Heart Antibodies  >19 publications with CPT1A and Heart
 Kidney Antibodies  >12 publications with CPT1A and Kidney
 Pancreas Antibodies  >7 publications with CPT1A and Pancreas
 Lung Antibodies  >4 publications with CPT1A and Lung
 Prostate Antibodies  >3 publications with CPT1A and Prostate
 Placenta Antibodies  >1 publications with CPT1A and Placenta
 Colon Antibodies  >1 publications with CPT1A and Colon
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000