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Myeloid Progenitor Inhibitory Factor 2 (MPIF2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2002547
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MBS2002547 is an antibody targeting MPIF2. Also known as Biotin-Linked Antibody to Myeloid Progenitor Inhibitory Factor 2 (MPIF2). Reactive in Rat, Human, Mouse. Host: Rabbit. More details

$220 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Myeloid Progenitor Inhibitory Factor 2 (MPIF2), Polyclonal Antibody
Full Product Name
Biotin-Linked Antibody to Myeloid Progenitor Inhibitory Factor 2 (MPIF2)
Product Gene Name
anti-MPIF2 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat, Human, Mouse
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against MPIF2 conjugated to biotin. It has been selected for its ability to recognize MPIF2 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Biotin Conjugated Antibody: MPIF2 (MBS2002547)
Immunogen: MPIF2 (MBS2011096)
Matching Pairs
Unconjugated Antibody: MPIF2 (MBS2005190)
Biotin Conjugated Antibody: MPIF2 (MBS2002547)
Molecular Weight
13,134 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (75440766..75452674, complement). Location: 7q11.23
OMIM
602495
3D Structure
ModBase 3D Structure for O00175
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Product Categories/Family for anti-MPIF2 antibody

Biotin Antibody
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-MPIF2 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes for anti-MPIF2 antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Other Notes

Small volumes of anti-MPIF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MPIF2. It may not necessarily be applicable to this product.

NCBI GI #
1916252
NCBI GeneID
6369
NCBI Accession #
AAB51135.1
UniProt Primary Accession #
O00175
UniProt Secondary Accession #
B2R5K2
UniProt Related Accession #
O00175
NCBI Official Full Name
MPIF-2
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 24
NCBI Official Symbol
CCL24
NCBI Official Synonym Symbols
Ckb-6; MPIF2; MPIF-2; SCYA24
UniProt Protein Name
C-C motif chemokine 24
UniProt Synonym Protein Names
CK-beta-6; Eosinophil chemotactic protein 2; Eotaxin-2; Myeloid progenitor inhibitory factor 2; MPIF-2; Small-inducible cytokine A24
UniProt Gene Name
CCL24
UniProt Synonym Gene Names
MPIF2; SCYA24; MPIF-2
UniProt Entry Name
CCL24_HUMAN
NCBI Protein Information
C-C motif chemokine 24; CK-beta-6; eotaxin-2; small-inducible cytokine A24; eosinophil chemotactic protein 2; myeloid progenitor inhibitory factor 2; small inducible cytokine subfamily A (Cys-Cys), member 24

NCBI Summary for MPIF2

This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2008]
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UniProt Comments for MPIF2

CCL24: Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: extracellular space

Molecular Function: chemokine activity

Biological Process: cytoskeleton organization and biogenesis; chemotaxis; signal transduction; regulation of cell shape; positive regulation of angiogenesis; cell-cell signaling; positive regulation of actin filament polymerization; eosinophil chemotaxis; positive regulation of endothelial cell proliferation; immune response; inflammatory response; positive regulation of cell migration; positive regulation of inflammatory response
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Research Articles on MPIF2

1. Pregnancy associated environments increased local CCL24/CCR3, supporting the process of decidualization in human early pregnancy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MPIF2 antibody

 Reference Product  PubMed Publications
 CCR3 antibody  >94 publications with MPIF2 and CCR3
 CCR5 antibody  >15 publications with MPIF2 and CCR5
 CCR2 antibody  >10 publications with MPIF2 and CCR2
 STAT6 antibody  >8 publications with MPIF2 and STAT6
 CXCR3 antibody  >7 publications with MPIF2 and CXCR3
 CCR1 antibody  >7 publications with MPIF2 and CCR1
 CCR8 antibody  >7 publications with MPIF2 and CCR8
 CXCR4 antibody  >5 publications with MPIF2 and CXCR4
 CXCR2 antibody  >2 publications with MPIF2 and CXCR2
 CXCR1 antibody  >1 publications with MPIF2 and CXCR1

Pathways associated with anti-MPIF2 antibody

 Products by Pathway  Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram

Diseases associated with anti-MPIF2 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >101 publications with MPIF2 and Inflammation
 Hypersensitivity Antibodies  >88 publications with MPIF2 and Hypersensitivity
 Asthma Antibodies  >87 publications with MPIF2 and Asthma
 Respiratory Tract Diseases Antibodies  >85 publications with MPIF2 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >77 publications with MPIF2 and Lung Diseases
 Respiratory Hypersensitivity Antibodies  >62 publications with MPIF2 and Respiratory Hypersensitivity
 Necrosis Antibodies  >24 publications with MPIF2 and Necrosis
 Dermatitis, Atopic Antibodies  >13 publications with MPIF2 and Dermatitis, Atopic
 Gastrointestinal Diseases Antibodies  >12 publications with MPIF2 and Gastrointestinal Diseases
 Fibrosis Antibodies  >10 publications with MPIF2 and Fibrosis

Organs/Tissues associated with anti-MPIF2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >10 publications with MPIF2 and Liver
 Intestine Antibodies  >7 publications with MPIF2 and Intestine
 Spleen Antibodies  >6 publications with MPIF2 and Spleen
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