Rabbit Anti-ANP32A Polyclonal Antibody – Cat# MBS2002586

Knockout Validation: Lane 1: Wild-type Hela cell lysate; Lane 2: ANP32A knockout Hela cell lysate; Predicted MW: 29kd Observed MW: 35kd Primary Ab: 1ug/ml Rabbit Anti-Human ANP32A Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047)

Acidic Nuclear Phosphoprotein 32 Family, Member A (ANP32A) Antibody – Rabbit Polyclonal

Name: ANP32A Antibody; Polyclonal; Rabbit; Human/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2002586
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2002586

MBS2002586 is an antibody targeting ANP32A. Also known as Biotin-Linked Antibody to Acidic Nuclear Phosphoprotein 32 Family, Member A (ANP32A). Reactive in Human, Rat. Host: Rabbit. More details

$225 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Acidic Nuclear Phosphoprotein 32 Family, Member A (ANP32A), Polyclonal Antibody

Full Product Name

Biotin-Linked Antibody to Acidic Nuclear Phosphoprotein 32 Family, Member A (ANP32A)

Product Gene Name

anti-ANP32A antibody

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human, Rat

Form/Format

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.

Purity/Purification

Affinity Chromatography

Concentration

500ug/ml (lot specific)

Specificity

The antibody is a rabbit polyclonal antibody raised against ANP32A conjugated to biotin. It has been selected for its ability to recognize ANP32A in immunohistochemical staining andwestern blotting.

Preparation and Storage

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Matching Pairs

Biotin Conjugated Antibody: ANP32A (MBS2002586)
Immunogen: ANP32A (MBS2009111)

Matching Pairs

Unconjugated Antibody: ANP32A (MBS2003917)
Biotin Conjugated Antibody: ANP32A (MBS2002586)

Molecular Weight

28,585 Da

Chromosome Location

Chromosome: 15; NC_000015.9 (69070874..69113261, complement). Location: 15q23

OMIM

600832

3D Structure

ModBase 3D Structure for P39687

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Product Categories/Family for anti-ANP32A antibody

Biotin Antibody

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-ANP32A antibody

Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)

Application Notes for anti-ANP32A antibody

Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Other Notes

Small volumes of anti-ANP32A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ANP32A. It may not necessarily be applicable to this product.

NCBI GI #

5453880

NCBI GeneID

8125

NCBI Accession #

NP_006296.1

UniProt Primary Accession #

P39687

UniProt Secondary Accession #

Q53FK4; Q5J8L8; Q7M4N6; B2R6T4

UniProt Related Accession #

P39687

GenBank Nucleotide #

NM_006305.3

NCBI Official Full Name

acidic leucine-rich nuclear phosphoprotein 32 family member A

NCBI Official Synonym Full Names

acidic (leucine-rich) nuclear phosphoprotein 32 family, member A

NCBI Official Symbol

ANP32A

NCBI Official Synonym Symbols

LANP; MAPM; PP32; HPPCn; PHAP1; PHAPI; I1PP2A; C15orf1

UniProt Protein Name

Acidic leucine-rich nuclear phosphoprotein 32 family member A

UniProt Synonym Protein Names

Acidic nuclear phosphoprotein pp32; Leucine-rich acidic nuclear protein; LANP; Mapmodulin; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; Putative HLA-DR-associated protein I

Protein Family

Acidic leucine-rich nuclear phosphoprotein 32 family

UniProt Gene Name

ANP32A

UniProt Synonym Gene Names

C15orf1; LANP; MAPM; PHAP1; LANP; PHAPI

UniProt Entry Name

AN32A_HUMAN

NCBI Protein Information

acidic leucine-rich nuclear phosphoprotein 32 family member A; mapmodulin; hepatopoietin Cn; acidic nuclear phosphoprotein pp32; leucine-rich acidic nuclear protein; putative HLA-DR-associated protein I; inhibitor-1 of protein phosphatase-2A; cerebellar leucine rich acidic nuclear protein; putative human HLA class II associated protein I; potent heat-stable protein phosphatase 2A inhibitor I1PP2A

UniProt Comments for ANP32A

ANP32A: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1- mediated transcriptional repression. Belongs to the ANP32 family.

Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 15q23

Cellular Component: nucleoplasm; endoplasmic reticulum; perinuclear region of cytoplasm; cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleocytoplasmic transport; gene expression

Research Articles on ANP32A

1. Demonstrate that HPPCn attenuated oxidative injury and fibrosis induced by ethanol feeding and that the SphK1/S1P/S1PRs signalling pathway contributes to this protective effect.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ANP32A antibody

Reference Product	PubMed Publications
SET antibody	>17 publications with ANP32A and SET
ELAVL1 antibody	>5 publications with ANP32A and ELAVL1
MAP1B antibody	>1 publications with ANP32A and MAP1B
ATXN1 antibody	>1 publications with ANP32A and ATXN1

Pathways associated with anti-ANP32A antibody

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway antibodies	Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway Diagram
Stabilization Of MRNA By HuR Pathway antibodies	Stabilization Of MRNA By HuR Pathway Diagram

Diseases associated with anti-ANP32A antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>13 publications with ANP32A and Neoplasms
Cell Transformation, Neoplastic Antibodies	>4 publications with ANP32A and Cell Transformation, Neoplastic
Ataxia Antibodies	>4 publications with ANP32A and Ataxia
Adenocarcinoma Antibodies	>2 publications with ANP32A and Adenocarcinoma
Prostatic Diseases Antibodies	>2 publications with ANP32A and Prostatic Diseases
Liver Diseases Antibodies	>2 publications with ANP32A and Liver Diseases
Liver Neoplasms Antibodies	>2 publications with ANP32A and Liver Neoplasms
Necrosis Antibodies	>2 publications with ANP32A and Necrosis
Gastrointestinal Diseases Antibodies	>1 publications with ANP32A and Gastrointestinal Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with ANP32A and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-ANP32A antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>18 publications with ANP32A and Brain
Nerve Antibodies	>13 publications with ANP32A and Nerve
Prostate Antibodies	>7 publications with ANP32A and Prostate
Blood Antibodies	>5 publications with ANP32A and Blood
Kidney Antibodies	>4 publications with ANP32A and Kidney
Liver Antibodies	>3 publications with ANP32A and Liver
Spleen Antibodies	>3 publications with ANP32A and Spleen
Ovary Antibodies	>3 publications with ANP32A and Ovary
Pituitary Gland Antibodies	>2 publications with ANP32A and Pituitary Gland
Pancreas Antibodies	>2 publications with ANP32A and Pancreas