Mouse Anti-ITLN1 Monoclonal Antibody – Cat# MBS200265

The lysate of 293T (60ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human ITLN1 antibody (1:250-1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

ITLN1 Antibody – Mouse Monoclonal

Name: ITLN1 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS200265
Price: 285 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200265

ITLN1, also known as intelectin1 or omentin, has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 may play a role in the defense system against microorganisms and specifically recognize carbohydrate chains… More details

$285 / 0.05 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ITLN1, Monoclonal Antibody

Full Product Name

ITLN1 antibody

Product Gene Name

anti-ITLN1 antibody

Product Synonym Names

Intelectin 1; HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin

Clonality

Monoclonal

Isotype

IgG1,kappa

Clone Number

AT6C11

Host

Mouse

Species Reactivity

Human

Form/Format

Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.

Purity/Purification

By protein-A affinity chromatography

Concentration

1mg/ml (lot specific)

Preparation and Storage

Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

34,962 Da

OMIM

AF271386 mRNA

3D Structure

ModBase 3D Structure for Q8WWA0

Antigen Species

Human

Immunogen

Recombinant human ITLN1 (17-313aa) purified from E. coli

Product Categories/Family for anti-ITLN1 antibody

Cardiovascular

Applications Tested/Suitable for anti-ITLN1 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-ITLN1 antibody

The antibody has been tested by ELISA and Western Blot analysis to assure specificity and reactivity. Since application varies , however, each investigation should be titrated by the reagent to obtain optimal results.

Product References and Citations for anti-ITLN1 antibody

Tsuji S., et al. (2001) J. Biol. Chem. 276:23456-23463. ; Tsuji S., et al. (2007) Glycobiology (10):1045-51

Other Notes

Small volumes of anti-ITLN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ITLN1 purchase

MBS200265 is an antibody targeting ITLN1. Also known as ITLN1 antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ITLN1. It may not necessarily be applicable to this product.

NCBI GI #

31542986

NCBI GeneID

55600

NCBI Accession #

NP_060095

UniProt Primary Accession #

Q8WWA0

UniProt Secondary Accession #

Q5IWS4; Q5VYI4; Q6YDJ3; Q9NP67

UniProt Related Accession #

Q8WWA0

GenBank Nucleotide #

NM_017625.2

NCBI Official Full Name

intelectin-1

NCBI Official Synonym Full Names

intelectin 1

NCBI Official Symbol

ITLN1

NCBI Official Synonym Symbols

HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin

UniProt Protein Name

Intelectin-1

UniProt Synonym Protein Names

Endothelial lectin HL-1; Galactofuranose-binding lectin; Intestinal lactoferrin receptor

Protein Family

Intelectin

UniProt Gene Name

ITLN1

UniProt Synonym Gene Names

INTL; ITLN; LFR; ITLN-1

NCBI Protein Information

intelectin-1

UniProt Comments for ITLN1

Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed:11313366, PubMed:26148048). Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) (PubMed:26148048). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris (PubMed:26148048). Does not bind human glycans (PubMed:26148048). Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed:16531507). Increases AKT phosphorylation in the absence and presence of insulin (PubMed:16531507). May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed:11747454, PubMed:23921499).

Research Articles on ITLN1

1. Omentin-1 levels are closely associated with the endogenous insulin reserve and may be used in follow-up of patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ITLN1 antibody

Reference Product	PubMed Publications
SERPINA12 antibody	>24 publications with ITLN1 and SERPINA12
IL13 antibody	>3 publications with ITLN1 and IL13
NAMPT antibody	>2 publications with ITLN1 and NAMPT
ITLN2 antibody	>2 publications with ITLN1 and ITLN2
RARRES2 antibody	>1 publications with ITLN1 and RARRES2

Pathways associated with anti-ITLN1 antibody

Products by Pathway	Pathway Diagram
Antimicrobial Peptides Pathway antibodies	Antimicrobial Peptides Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Diseases associated with anti-ITLN1 antibody

Disease Name	Pubmed Publications
Insulin Resistance Antibodies	>80 publications with ITLN1 and Insulin Resistance
Cardiovascular Diseases Antibodies	>75 publications with ITLN1 and Cardiovascular Diseases
Inflammation Antibodies	>51 publications with ITLN1 and Inflammation
Diabetes Mellitus Antibodies	>50 publications with ITLN1 and Diabetes Mellitus
Diabetes Mellitus, Type 2 Antibodies	>39 publications with ITLN1 and Diabetes Mellitus, Type 2
Heart Diseases Antibodies	>31 publications with ITLN1 and Heart Diseases
Atherosclerosis Antibodies	>30 publications with ITLN1 and Atherosclerosis
Necrosis Antibodies	>21 publications with ITLN1 and Necrosis
Lung Diseases Antibodies	>11 publications with ITLN1 and Lung Diseases
Weight Loss Antibodies	>7 publications with ITLN1 and Weight Loss

Organs/Tissues associated with anti-ITLN1 antibody

Organ/Tissue Name	Pubmed Publications
Adipose Tissue Antibodies	>92 publications with ITLN1 and Adipose Tissue
Vascular Antibodies	>43 publications with ITLN1 and Vascular
Heart Antibodies	>27 publications with ITLN1 and Heart
Muscle Antibodies	>16 publications with ITLN1 and Muscle
Intestine Antibodies	>16 publications with ITLN1 and Intestine
Lung Antibodies	>14 publications with ITLN1 and Lung
Kidney Antibodies	>6 publications with ITLN1 and Kidney
Brain Antibodies	>6 publications with ITLN1 and Brain
Stomach Antibodies	>3 publications with ITLN1 and Stomach