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CRLF2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200266

CRLF2 is cytokine receptor-like factor 2. Cytokine signals are mediated through specific receptor complexes, the components of which are mostly members of the type I cytokine receptor family. Type I cytokine receptors share conserved structural features in… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Product Overview

Product Name
CRLF2, Monoclonal Antibody
Full Product Name
CRLF2 antibody
Product Gene Name
Product Synonym Names
Cytokine receptor-like factor 2 isoform 1 precursor; CRL2; CRLF2Y; TSLPR
Clonality
Monoclonal
Isotype
IgG2a, k
Clone Number
AT4E7
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
Purity/Purification
By protein-A affinity chromatography
Concentration
1mg/ml (lot specific)
Preparation and Storage
Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
29,360 Da
OMIM
AF142570 mRNA
3D Structure
ModBase 3D Structure for Q9HC73
Antigen Species
Human
Immunogen
Recombinant human CRLF2 (23-231aa) purified from E. coli
Clone Note
Anti-human CRLF2 mAb, clone AT4E7, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CRLF2 protein.

Product Categories/Family for anti-CRLF2 antibody

Applications Tested/Suitable for anti-CRLF2 antibody
ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-CRLF2 antibody
WB: 1:500 ~ 1:5000.
Recommended starting dilution is 1:1000.

Western Blot (WB) of anti-CRLF2 antibody

The cell lysate of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CRLF2 antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Mouse Anti-CRLF2 Monoclonal Antibody – Cat# MBS200266

Product References and Citations for anti-CRLF2 antibody

Blagoev B, Nielsen MM, Angrist M, et al. (2002). Gene 284 (1-2): 161-8.; Reche PA, Soumelis V, Gorman DM, et al. (2001). J. Immunol. 167 (1): 336-43.

Other Notes

Small volumes of anti-CRLF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CRLF2 purchase

MBS200266 is an antibody targeting CRLF2. Also known as CRLF2 antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CRLF2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
GenBank Nucleotide #
NCBI Official Full Name
cytokine receptor-like factor 2 isoform 1
UniProt Protein Name
Cytokine receptor-like factor 2
UniProt Synonym Protein Names
Cytokine receptor-like 2; IL-XR; Thymic stromal lymphopoietin protein receptor; TSLP receptor
UniProt Gene Name
CRLF2
UniProt Synonym Gene Names
CRL2; ILXR; TSLPR; TSLP receptor

UniProt Comments for CRLF2

Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (). Implicated in the development of the hematopoietic system.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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