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Alpha-Fodrin (SPTAN1) Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2002742
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2002742 is an antibody targeting SPTAN1. Also known as Polyclonal Antibody to Alpha-Fodrin (SPTAN1). Reactive in Mouse, Human, Rat. Host: Rabbit. More details

$205 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Alpha-Fodrin (SPTAN1), Antibody
Full Product Name
Polyclonal Antibody to Alpha-Fodrin (SPTAN1)
Product Gene Name
anti-SPTAN1 antibody
Host
Rabbit
Species Reactivity
Mouse, Human, Rat
Form/Format
Liquid; Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
0.3mg/ml (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 24 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: SPTAN1 (MBS2002742)
Immunogen: SPTAN1 (MBS2009757)
Matching Pairs
Unconjugated Antibody: SPTAN1 (MBS2002742)
APC-CY7 Conjugated Antibody: SPTAN1 (MBS2040602)
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3D Structure
ModBase 3D Structure for P16546
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Cross Reactivity
Human; Rat
Immunogen
Recombinant SPTAN1 (Ile1049~Ser1207 (Accession # P16546)) expressed in E.coli (MBS2009757)
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-SPTAN1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-SPTAN1 antibody
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-SPTAN1 antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-SPTAN1 Antibody – Cat# MBS2002742

Immunohistochemistry (IHC) of anti-SPTAN1 antibody

DAB staining on IHC-P; Samples: Mouse
Kidney Tissue; Primary Ab: 20?g/ml Rabbit Anti-Mouse SPTAN1 Antibody
Second Ab: 2µg/mL HRP-Linked Caprine
Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047)
Rabbit Anti-SPTAN1 Antibody, Immunohistochemistry (IHC) – Cat# MBS2002742

Other Notes

Small volumes of anti-SPTAN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SPTAN1. It may not necessarily be applicable to this product.

NCBI GI #
122066202
NCBI GeneID
20740
UniProt Primary Accession #
P16546
UniProt Secondary Accession #
Q8K380; Q9CT05; A3KGU6; A3KGU8
UniProt Related Accession #
P16546
NCBI Official Full Name
Spectrin alpha chain, non-erythrocytic 1
NCBI Official Synonym Full Names
spectrin alpha, non-erythrocytic 1
NCBI Official Symbol
Sptan1
NCBI Official Synonym Symbols
Spna2; Spna-2; 2610027H02Rik
UniProt Protein Name
Spectrin alpha chain, non-erythrocytic 1
UniProt Synonym Protein Names
Alpha-II spectrin; Fodrin alpha chain
Protein Family
Spectrin
UniProt Gene Name
Sptan1
UniProt Synonym Gene Names
Spna2; Spta2
NCBI Protein Information
spectrin alpha chain, non-erythrocytic 1

UniProt Comments for SPTAN1

SPTAN1: a cytoskeletal protein which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Capable to forming dimers which can further associate to tetramers.

Protein type: Adaptor/scaffold; Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2 B|2 20.93 cM

Cellular Component: cortical cytoskeleton; cytoplasm; cytoskeleton; extracellular exosome; fascia adherens; intracellular membrane-bound organelle; lateral plasma membrane; membrane; microtubule cytoskeleton; myelin sheath; paranode region of axon; plasma membrane; protein complex; Z disc

Molecular Function: actin binding; cadherin binding; calcium ion binding; calmodulin binding; metal ion binding; protein binding; protein complex binding; protein heterodimerization activity; protein N-terminus binding; spectrin binding; syntaxin binding

Biological Process: actin cytoskeleton reorganization; actin filament capping
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Research Articles on SPTAN1

1. Fodrin is a regulatory transporter of gamma-tubulin to the centrosomes for normal progression of mitosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SPTAN1 antibody

 Reference Product  PubMed Publications
 Casp3 antibody  >2 publications with SPTAN1 and Casp3
 Actn4 antibody  >1 publications with SPTAN1 and Actn4

Pathways associated with anti-SPTAN1 antibody

 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 COPI-mediated Anterograde Transport Pathway antibodies  COPI-mediated Anterograde Transport Pathway Diagram
 Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies  Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram

Organs/Tissues associated with anti-SPTAN1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with SPTAN1 and Brain
 Blood Antibodies  >4 publications with SPTAN1 and Blood
 Lung Antibodies  >2 publications with SPTAN1 and Lung
 Stomach Antibodies  >1 publications with SPTAN1 and Stomach
 Heart Antibodies  >1 publications with SPTAN1 and Heart
 Skin Antibodies  >1 publications with SPTAN1 and Skin
 Intestine Antibodies  >1 publications with SPTAN1 and Intestine
 Muscle Antibodies  >1 publications with SPTAN1 and Muscle
 Eye Antibodies  >1 publications with SPTAN1 and Eye
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