Mouse Anti-SSR4 Monoclonal Antibody – Cat# MBS200275

The lysate of MCF7 (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SSR4 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

SSR4 Antibody – Mouse Monoclonal

Name: SSR4 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS200275
Price: 285 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200275

SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode… More details

$285 / 0.05 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SSR4, Monoclonal Antibody

Full Product Name

SSR4 antibody

Product Gene Name

anti-SSR4 antibody

Product Synonym Names

Translocon-associated protein subunit delta; TRAPD

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

AT26G5

Host

Mouse

Species Reactivity

Human

Form/Format

Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.

Purity/Purification

By protein-A affinity chromatography

Concentration

1mg/ml (lot specific)

Preparation and Storage

Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

18,999 Da

OMIM

X90583 mRNA

3D Structure

ModBase 3D Structure for P51571

Antigen Species

Human

Immunogen

Recombinant human SSR4 (24-144aa) purified from E. coli

Clone Note

Anti-human SSR4 mAb, clone AT26G5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SSR4 protein.

Product Categories/Family for anti-SSR4 antibody

Signal Transduction

Applications Tested/Suitable for anti-SSR4 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-SSR4 antibody

Recommended starting dilution is 1:1000.

Product References and Citations for anti-SSR4 antibody

Brenner V., et al. (1997) Genomics 44 (1): 8-14; Holthuis JC., et al. (1996) J Biol Chem 312 (Pt 1) (Pt 1): 205-13; Entrez Gene: SSR4 signal sequence receptor, delta

Other Notes

Small volumes of anti-SSR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SSR4 purchase

MBS200275 is an antibody targeting SSR4. Also known as SSR4 antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SSR4. It may not necessarily be applicable to this product.

NCBI GI #

5454090

NCBI GeneID

6748

NCBI Accession #

NP_006271

UniProt Primary Accession #

P51571

UniProt Secondary Accession #

Q53XY1; A8K378

UniProt Related Accession #

P51571

GenBank Nucleotide #

NM_006280.2

NCBI Official Full Name

translocon-associated protein subunit delta isoform 2

NCBI Official Synonym Full Names

signal sequence receptor subunit 4

NCBI Official Symbol

SSR4

NCBI Official Synonym Symbols

CDG1Y; TRAPD

UniProt Protein Name

Translocon-associated protein subunit delta

UniProt Synonym Protein Names

Signal sequence receptor subunit delta; SSR-delta

Protein Family

SWI/SNF and RSC complexes

UniProt Gene Name

SSR4

UniProt Synonym Gene Names

TRAPD; TRAP-delta; SSR-delta

NCBI Protein Information

translocon-associated protein subunit delta

NCBI Summary for SSR4

This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane. The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011]

UniProt Comments for SSR4

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

Research Articles on SSR4

1. We now report eight affected males with either de novo (4) or inherited (4) loss of function mutations in SSR4.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SSR4 antibody

Reference Product	PubMed Publications
DDOST antibody	>1 publications with SSR4 and DDOST
SSR2 antibody	>1 publications with SSR4 and SSR2
SSR3 antibody	>1 publications with SSR4 and SSR3

Pathways associated with anti-SSR4 antibody

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram
SRP-dependent Cotranslational Protein Targeting To Membrane Pathway antibodies	SRP-dependent Cotranslational Protein Targeting To Membrane Pathway Diagram
Translation Pathway antibodies	Translation Pathway Diagram
Translocon-associated Protein (TRAP) Complex Pathway antibodies	Translocon-associated Protein (TRAP) Complex Pathway Diagram
Translocon-associated Protein (TRAP) Complex Pathway antibodies	Translocon-associated Protein (TRAP) Complex Pathway Diagram

Diseases associated with anti-SSR4 antibody

Disease Name	Pubmed Publications
Fibrosis Antibodies	>2 publications with SSR4 and Fibrosis
Nervous System Diseases Antibodies	>1 publications with SSR4 and Nervous System Diseases
Fatty Liver Antibodies	>1 publications with SSR4 and Fatty Liver
Inflammation Antibodies	>1 publications with SSR4 and Inflammation

Organs/Tissues associated with anti-SSR4 antibody

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>2 publications with SSR4 and Eye
Thymus Antibodies	>1 publications with SSR4 and Thymus
Connective Tissue Antibodies	>1 publications with SSR4 and Connective Tissue
Stomach Antibodies	>1 publications with SSR4 and Stomach
Blood Antibodies	>1 publications with SSR4 and Blood
Adrenal Gland Antibodies	>1 publications with SSR4 and Adrenal Gland
Liver Antibodies	>1 publications with SSR4 and Liver
Pancreas Antibodies	>1 publications with SSR4 and Pancreas
Brain Antibodies	>1 publications with SSR4 and Brain