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Cathepsin G (CTSG) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2002863
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MBS2002863 is an antibody targeting CTSG. Also known as Polyclonal Antibody to Cathepsin G (CTSG). Reactive in Human, Mouse. Host: Rabbit. More details

$215 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cathepsin G (CTSG), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Cathepsin G (CTSG)
Product Gene Name
anti-CTSG antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Concentration
0.67mg/ml (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: CTSG (MBS2002863)
Biotin Conjugated Antibody: CTSG (MBS2008564)
Matching Pairs
Unconjugated Antibody: CTSG (MBS2002863)
FITC Conjugated Antibody: CTSG (MBS2017770)
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3D Structure
ModBase 3D Structure for P28293
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Traits
Liquid
Cross Reactivity
Human, Mouse
Immunogen
Recombinant CTSG (Ile21~Thr261) expressed in E.coli (MBS2029904).
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CTSG antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP).
Application Notes for anti-CTSG antibody
Western blotting: 0.5-3ug/mL
Immunohistochemistry: 5-30ug/mL
Immunocytochemistry: 5-30ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-CTSG antibody

Western Blot:
Sample: Recombinant CTSG, Mouse.
Rabbit Anti-CTSG Polyclonal Antibody – Cat# MBS2002863

Western Blot (WB) of anti-CTSG antibody

Western Blot: Sample: Human MCF7 cell lysate;
Primary Ab: 3ug/ml Rabbit Anti-Mouse CTSG Antibody
Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047)
Rabbit Anti-CTSG Polyclonal Antibody, Western Blot (WB) – Cat# MBS2002863

Immunohistochemistry (IHC) of anti-CTSG antibody

DAB staining on IHC-P;
Samples: Mouse Spinal cord Tissue;
Primary Ab: 10ug/ml Rabbit Anti-Mouse CTSG Antibody
Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047)
Rabbit Anti-CTSG Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2002863

Immunohistochemistry (IHC) of anti-CTSG antibody

DAB staining on IHC-P.
Samples: Mouse Tissue
Rabbit Anti-CTSG Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2002863

Other Notes

Small volumes of anti-CTSG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CTSG. It may not necessarily be applicable to this product.

NCBI GI #
6681083
NCBI GeneID
13035
NCBI Accession #
NP_031826.1
UniProt Primary Accession #
P28293
UniProt Related Accession #
P28293
GenBank Nucleotide #
NM_007800.2
NCBI Official Full Name
cathepsin G preproprotein
NCBI Official Synonym Full Names
cathepsin G
NCBI Official Symbol
Ctsg
NCBI Official Synonym Symbols
VSP; CatG
UniProt Protein Name
Cathepsin G
UniProt Synonym Protein Names
Vimentin-specific protease; VSP
Protein Family
Cathepsin
UniProt Gene Name
Ctsg
UniProt Synonym Gene Names
VSP
NCBI Protein Information
cathepsin G

NCBI Summary for CTSG

This gene encodes a member of the peptidase S1 (chymotrypsin) family of serine endopeptidases. The encoded preproprotein is proteolytically processed to generate a mature protein product. This product appears to play a role in host defense, including inflammation and antigen processing. Homozygous knockout mice for this gene exhibit enhanced susceptibility to bacterial and fungal infection. [provided by RefSeq, Aug 2015]
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UniProt Comments for CTSG

CTSG: Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. Belongs to the peptidase S1 family.

Protein type: EC 3.4.21.20; Motility/polarity/chemotaxis; Protease

Chromosomal Location of Human Ortholog: 14 C3|14 28.19 cM

Cellular Component: extracellular matrix; extracellular space; intermediate filament; membrane; nucleus; plasma membrane; secretory granule; stress granule

Molecular Function: heparin binding; hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: antibacterial humoral response; defense response to fungus; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; positive regulation of immune response; protein amino acid phosphorylation; proteolysis; response to lipopolysaccharide
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Research Articles on CTSG

1. these findings present evidence of an arterial-specific recruitment pattern centered on CatG-instructed adhesion strengthening. The inhibition of this process could provide a novel strategy for treatment of arterial inflammation with limited side effects.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CTSG antibody

 Reference Product  PubMed Publications
 Agt antibody  >1 publications with CTSG and Agt

Pathways associated with anti-CTSG antibody

 Products by Pathway  Pathway Diagram
 Activation Of Matrix Metalloproteinases Pathway antibodies  Activation Of Matrix Metalloproteinases Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies  Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with anti-CTSG antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >148 publications with CTSG and Inflammation
 Lung Diseases Antibodies  >61 publications with CTSG and Lung Diseases
 Cardiovascular Diseases Antibodies  >46 publications with CTSG and Cardiovascular Diseases
 Leukemia Antibodies  >37 publications with CTSG and Leukemia
 Necrosis Antibodies  >33 publications with CTSG and Necrosis
 Fibrosis Antibodies  >28 publications with CTSG and Fibrosis
 Kidney Diseases Antibodies  >10 publications with CTSG and Kidney Diseases
 Carcinoma Antibodies  >10 publications with CTSG and Carcinoma
 Hemorrhage Antibodies  >10 publications with CTSG and Hemorrhage
 Breast Neoplasms Antibodies  >6 publications with CTSG and Breast Neoplasms

Organs/Tissues associated with anti-CTSG antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >626 publications with CTSG and Blood
 Bone Antibodies  >44 publications with CTSG and Bone
 Bone Marrow Antibodies  >32 publications with CTSG and Bone Marrow
 Spleen Antibodies  >7 publications with CTSG and Spleen
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