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CREG1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200294

CREG1 activity may contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. CREG1 is broadly expressed in adult tissues and is regulated… More details

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Product Overview

Product Name
CREG1, Monoclonal Antibody
Full Product Name
CREG1 antibody
Product Gene Name
Product Synonym Names
Cellular repressor of E1A-stimulated genes 1; CREG
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
AT1C6
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
Purity/Purification
By protein-A affinity chromatography
Concentration
1mg/ml (lot specific)
Preparation and Storage
Can be stored at 2-8 degree C for 1 week.
For long term storage, aliquot and store at -20 to -80 degree C.
Avoid repeated freezing and thawing cycles.
3D Structure
ModBase 3D Structure for O75629
Antigen Species
Human
Immunogen
Recombinant human CREG1 (32-220aa) purified from E. coli
Clone Note
Anti-human CREG1 mAb, clone AT1C6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CREG1 protein.

Product Categories/Family for anti-CREG1 antibody

Applications Tested/Suitable for anti-CREG1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-CREG1 antibody
Recommended starting dilution is 1:1000.

Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Western Blot (WB) of anti-CREG1 antibody

Fig. 1: The tissue extract of mouse lung (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CREG1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Fig. 2: The Recombinant Human CREG1 (50ng) protein were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CREG1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Mouse Anti-CREG1 Monoclonal Antibody – Cat# MBS200294

Product References and Citations for anti-CREG1 antibody

Veal E., et al. (1998) Mol Cell Biol 18 (9): 5032-5041; Veal E., et al. (2000) Oncogene 19 (17): 2120-2128

Other Notes

Small volumes of anti-CREG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CREG1 purchase

MBS200294 is an antibody targeting CREG1. Also known as CREG1 antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CREG1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein CREG1
NCBI Official Synonym Full Names
cellular repressor of E1A stimulated genes 1
NCBI Official Symbol
CREG1
NCBI Official Synonym Symbols
CREG
UniProt Protein Name
Protein CREG1
UniProt Synonym Protein Names
Cellular repressor of E1A-stimulated genes 1
Protein Family
UniProt Gene Name
CREG1
UniProt Synonym Gene Names
CREG
NCBI Protein Information
protein CREG1

NCBI Summary for CREG1

The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq, Jul 2008]
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UniProt Comments for CREG1

May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires interaction with IGF2R.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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