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Inter Alpha-Globulin Inhibitor H1 (ITIH1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2002960
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MBS2002960 is an antibody targeting ITIH1. Also known as Polyclonal Antibody to Inter Alpha-Globulin Inhibitor H1 (ITIH1). Reactive in Mouse. Host: Rabbit. More details

$215 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Inter Alpha-Globulin Inhibitor H1 (ITIH1), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Inter Alpha-Globulin Inhibitor H1 (ITIH1)
Product Gene Name
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS-ILKNV RNA IRGRFPLYNL GFGHDLDFSF LEVMSTENNG WAQRIYEDHD ATQQLQGFYN QVANPLLTDV ELQYPQDAVL ALTQHRHKQY YDGSEIVVAG RIANHKLNTF KADVRARGEK QEFRATCLVD EEEMKKLLRE RGHVLENHVE RLWAYLTIQE LLAKRMKTEG EERANLSSQV LKMSLDYHFV TPLTSLTIRG LTDEDGLEPT IDKPLEDSQP LEMVGPRRTF VLSAIQPSPT AHPIDSKLPL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against ITIH1. It has been selected for its ability to recognize ITIH1 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: ITIH1 (MBS2002960)
Immunogen: ITIH1 (MBS2009485)
Matching Pairs
Unconjugated Antibody: ITIH1 (MBS2002960)
APC-CY7 Conjugated Antibody: ITIH1 (MBS2080366)
Molecular Weight
101,067 Da
3D Structure
ModBase 3D Structure for Q61702
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant ITIH1 (Ile413~Leu660) expressed in E.coli.
Cross Reactivity
Mouse
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2080368
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-ITIH1 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-ITIH1 antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-ITIH1 antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-ITIH1 Polyclonal Antibody – Cat# MBS2002960

Immunohistochemistry (IHC) of anti-ITIH1 antibody

DABstainingonIHC-P.Samples:MouseTissue)
Rabbit Anti-ITIH1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2002960

Other Notes

Small volumes of anti-ITIH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ITIH1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
inter-alpha-trypsin inhibitor heavy chain H1 isoform 2
NCBI Official Synonym Full Names
inter-alpha trypsin inhibitor, heavy chain 1
NCBI Official Symbol
Itih1
NCBI Official Synonym Symbols
Intin1; Itih-1; ITI-HC1
UniProt Protein Name
Inter-alpha-trypsin inhibitor heavy chain H1
UniProt Gene Name
Itih1
UniProt Synonym Gene Names
ITI heavy chain H1; ITI-HC1; Inter-alpha-inhibitor heavy chain 1
NCBI Protein Information
inter-alpha-trypsin inhibitor heavy chain H1

NCBI Summary for ITIH1

This gene encodes a heavy chain of inter-alpha trypsin inhibitor (IaI) family of plasma serine protease inhibitors. IaI proteins are protein-glycosaminoglycan-protein complexes comprised of two heavy chains and a light chain. The encoded protein covalently associates with the light chain via a chondroitin sulfate moiety. Intravenous administration of the encoded protein improved survival of mice after infection with Escherichia coli. This gene is located adjacent to two other IaI heavy chain genes. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature protein. [provided by RefSeq, Oct 2015]
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UniProt Comments for ITIH1

ITIH1: May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. Belongs to the ITIH family.

Protein type: Inhibitor; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14|14 B

Cellular Component: blood microparticle; extracellular exosome; extracellular region

Molecular Function: peptidase inhibitor activity; serine-type endopeptidase inhibitor activity

Biological Process: hyaluronan metabolic process; negative regulation of peptidase activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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