• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Interleukin 2 Receptor Beta (IL2Rb) Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2002997
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2002997 is an antibody targeting IL2Rb. Also known as Polyclonal Antibody to Interleukin 2 Receptor Beta (IL2Rb). Reactive in Human, Mouse. Host: Rabbit. More details

$205 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interleukin 2 Receptor Beta (IL2Rb), Antibody
Full Product Name
Polyclonal Antibody to Interleukin 2 Receptor Beta (IL2Rb)
Product Gene Name
anti-IL2Rb antibody
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Concentration
0.37mg/ml (lot specific)
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 24 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: IL2Rb (MBS2002997)
Immunogen: IL2Rb (MBS2010767)
Matching Pairs
Unconjugated Antibody: IL2Rb (MBS2002997)
APC-CY7 Conjugated Antibody: IL2Rb (MBS2039915)
Show more
3D Structure
ModBase 3D Structure for P16297
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Organism Species
Mus musculus (Mouse)
Source
Polyclonal antibody preparation
Traits
Liquid
Cross Reactivity
Human, Mouse
Immunogen
Recombinant IL2Rb (Ala27~Glu240) expressed in E.coli (MBS2010767).
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-IL2Rb antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-IL2Rb antibody
Western blotting: 0.5-3ug/mL
Immunohistochemistry: 5-30ug/mL
Immunocytochemistry: 5-30ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-IL2Rb antibody

Western Blot: Sample: Human 293T cell lysate; Primary Ab: 3ug/ml Rabbit Anti-Mouse IL2Rb Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;
Rabbit Anti-IL2Rb Antibody – Cat# MBS2002997

Western Blot (WB) of anti-IL2Rb antibody

Western Blot: Sample: Human Hela cell lysate; Primary Ab: 3ug/ml Rabbit Anti-Mouse IL2Rb Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;(MBS2086047)
Rabbit Anti-IL2Rb Antibody, Western Blot (WB) – Cat# MBS2002997

Western Blot (WB) of anti-IL2Rb antibody

Figure. Western Blot; Sample: Recombinant IL2Rb, Mouse.
Rabbit Anti-IL2Rb Antibody, Western Blot (WB) – Cat# MBS2002997

Immunohistochemistry (IHC) of anti-IL2Rb antibody

DAB staining on IHC-P. Samples: Mouse Tissue)
Rabbit Anti-IL2Rb Antibody, Immunohistochemistry (IHC) – Cat# MBS2002997

Other Notes

Small volumes of anti-IL2Rb antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL2Rb. It may not necessarily be applicable to this product.

NCBI GI #
6680427
NCBI GeneID
16185
NCBI Accession #
NP_032394.1
UniProt Primary Accession #
P16297
UniProt Secondary Accession #
Q3TZT2
UniProt Related Accession #
P16297
GenBank Nucleotide #
NM_008368.4
NCBI Official Full Name
interleukin-2 receptor subunit beta
NCBI Official Synonym Full Names
interleukin 2 receptor, beta chain
NCBI Official Symbol
Il2rb
NCBI Official Synonym Symbols
p70; CD122; IL15Rbeta; Il-2Rbeta; IL-15Rbeta; Il-2/15Rbeta
UniProt Protein Name
Interleukin-2 receptor subunit beta
UniProt Synonym Protein Names
High affinity IL-2 receptor subunit beta; p70-75; CD_antigen: CD122
Protein Family
Interleukin-2 receptor
UniProt Gene Name
Il2rb
UniProt Synonym Gene Names
IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB
NCBI Protein Information
interleukin-2 receptor subunit beta

NCBI Summary for IL2Rb

The interleukin 2 receptor is composed of alpha and beta subunits. The beta subunit encoded by this gene is very homologous to the human beta subunit and also shows structural similarity to other cytokine receptors. [provided by RefSeq, Jul 2008]

UniProt Comments for IL2Rb

IL2RB: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation. Interacts with HTLV-1 accessory protein p12I. Belongs to the type I cytokine receptor family. Type 4 subfamily.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 15 E1|15 37.52 cM

Cellular Component: cell surface; external side of plasma membrane; integral component of membrane; membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-2 binding; interleukin-2 receptor activity

Biological Process: cytokine-mediated signaling pathway; natural killer cell activation; negative regulation of apoptosis
Show more

Research Articles on IL2Rb

1. c-REL, but not IkappaBNS, controlled the generation of classical CD25(+)Foxp3(-) precursors via direct binding to the Cd25 locus; propose that CD4(+)GITR(+)CD122(+)CD25(-)Foxp3(-) cells represent a Treg pre-precursor population, whose transition into Treg precursors is mediated via c-REL

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL2Rb antibody

 Reference Product  PubMed Publications
 Il15 antibody  >30 publications with IL2Rb and Il15
 Il2ra antibody  >23 publications with IL2Rb and Il2ra
 Il2rg antibody  >10 publications with IL2Rb and Il2rg
 Jak3 antibody  >6 publications with IL2Rb and Jak3
 Jak1 antibody  >6 publications with IL2Rb and Jak1
 Jak2 antibody  >3 publications with IL2Rb and Jak2
 Shc1 antibody  >2 publications with IL2Rb and Shc1
 Syk antibody  >1 publications with IL2Rb and Syk

Pathways associated with anti-IL2Rb antibody

 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Of Activated FGFR1 Pathway antibodies  Downstream Signaling Of Activated FGFR1 Pathway Diagram

Diseases associated with anti-IL2Rb antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >25 publications with IL2Rb and Inflammation
 Arthritis, Rheumatoid Antibodies  >12 publications with IL2Rb and Arthritis, Rheumatoid
 Necrosis Antibodies  >10 publications with IL2Rb and Necrosis
 Hypersensitivity Antibodies  >10 publications with IL2Rb and Hypersensitivity
 Asthma Antibodies  >9 publications with IL2Rb and Asthma
 Lung Diseases Antibodies  >9 publications with IL2Rb and Lung Diseases
 Liver Diseases Antibodies  >7 publications with IL2Rb and Liver Diseases
 Adenocarcinoma Antibodies  >4 publications with IL2Rb and Adenocarcinoma
 Chromosome Aberrations Antibodies  >4 publications with IL2Rb and Chromosome Aberrations
 Neoplasms, Experimental Antibodies  >4 publications with IL2Rb and Neoplasms, Experimental

Organs/Tissues associated with anti-IL2Rb antibody

 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >13 publications with IL2Rb and Spleen
 Bone Antibodies  >11 publications with IL2Rb and Bone
 Liver Antibodies  >8 publications with IL2Rb and Liver
 Lung Antibodies  >7 publications with IL2Rb and Lung
 Thymus Antibodies  >7 publications with IL2Rb and Thymus
 Intestine Antibodies  >4 publications with IL2Rb and Intestine
 Heart Antibodies  >3 publications with IL2Rb and Heart
 Pancreas Antibodies  >1 publications with IL2Rb and Pancreas
 Embryonic Tissue Antibodies  >1 publications with IL2Rb and Embryonic Tissue
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000