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Alanine Aminotransferase 2 (ALT2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2003176
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MBS2003176 is an antibody targeting ALT2. Also known as Biotin-Linked Antibody to Alanine Aminotransferase 2 (ALT2). Reactive in Human, Mouse, Rat, Pig. Host: Rabbit. More details

$225 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Alanine Aminotransferase 2 (ALT2), Polyclonal Antibody
Full Product Name
Biotin-Linked Antibody to Alanine Aminotransferase 2 (ALT2)
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Pig
Form/Format
Supplied as solution form in PBS, pH7.4, 50% glycerol; 0.05% Proclin-300.
Purity/Purification
Antigen-specific Affinity Chromatography.
Concentration
1mg/ml (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Biotin Conjugated Antibody: ALT2 (MBS2003176)
Immunogen: ALT2 (MBS2012004)
Matching Pairs
Unconjugated Antibody: ALT2 (MBS2003843)
Biotin Conjugated Antibody: ALT2 (MBS2003176)
Chromosome Location
Chromosome: 16; NC_000016.9 (46918308..46965201). Location: 16q12.1
OMIM
138210
3D Structure
ModBase 3D Structure for Q8TD30
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Antibody labeling
Label
Biotin
Unconjugated Antibody
Traits
Liquid
Immunogen
Recombinant ALT2 (Met210~Glu300) expressed in E.coli ( MBS2012004 ).

Product Categories/Family for anti-ALT2 antibody

ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-ALT2 antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP).
Application Notes for anti-ALT2 antibody
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Other Notes

Small volumes of anti-ALT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ALT2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
alanine aminotransferase 2 isoform 2
NCBI Official Synonym Full Names
glutamic pyruvate transaminase (alanine aminotransferase) 2
NCBI Official Symbol
GPT2
NCBI Official Synonym Symbols
ALT2
UniProt Protein Name
Alanine aminotransferase 2
UniProt Synonym Protein Names
Glutamate pyruvate transaminase 2; GPT 2; Glutamic--alanine transaminase 2; Glutamic--pyruvic transaminase 2
UniProt Gene Name
GPT2
UniProt Synonym Gene Names
AAT2; ALT2; ALT2; GPT 2
UniProt Entry Name
ALAT2_HUMAN
NCBI Protein Information
alanine aminotransferase 2; GPT 2; glutamic--alanine transaminase 2; glutamic--pyruvic transaminase 2; glutamic-pyruvate transaminase 2; glutamate pyruvate transaminase 2

NCBI Summary for ALT2

This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
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UniProt Comments for ALT2

GPT2: Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Transferase; Amino Acid Metabolism - alanine, aspartate and glutamate; EC 2.6.1.2

Chromosomal Location of Human Ortholog: 16q12.1

Cellular Component: mitochondrial matrix

Molecular Function: alanine transaminase activity; pyridoxal phosphate binding

Biological Process: amino acid biosynthetic process; L-alanine metabolic process; L-alanine catabolic process; 2-oxoglutarate metabolic process

Disease: Mental Retardation, Autosomal Recessive 49
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ALT2 antibody

 Reference Product  PubMed Publications
 LDHB antibody  >1 publications with ALT2 and LDHB
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