Catalase (CAT) Antibody – Rabbit Polyclonal

Catalase: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. Homotetramer. Belongs to the catalase family.

Protein type: Amino Acid Metabolism - tryptophan; Apoptosis; EC 1.11.1.6; Endoplasmic reticulum; Energy Metabolism - methane; Hydrolase; Mitochondrial; Oxidoreductase

Chromosomal Location of Human Ortholog: 2 E2|2 54.43 cM

Cellular Component: cytosol; endoplasmic reticulum; extracellular exosome; extracellular space; focal adhesion; Golgi apparatus; intracellular membrane-bound organelle; lysosome; membrane; mitochondrial intermembrane space; mitochondrion; peroxisomal membrane; peroxisome; plasma membrane

Molecular Function: aminoacylase activity; antioxidant activity; catalase activity; enzyme binding; heme binding; metal ion binding; NADP binding; oxidoreductase activity; oxidoreductase activity, acting on peroxide as acceptor; peroxidase activity; protein homodimerization activity; receptor binding

Biological Process: aerobic respiration; cholesterol metabolic process; hemoglobin metabolic process; hydrogen peroxide catabolic process; kidney development; negative regulation of apoptosis; negative regulation of NF-kappaB transcription factor activity; osteoblast differentiation; positive regulation of cell division; positive regulation of NF-kappaB transcription factor activity; positive regulation of phosphoinositide 3-kinase cascade; protein homotetramerization; protein tetramerization; response to hydrogen peroxide; response to hypoxia; response to oxidative stress; response to reactive oxygen species; triacylglycerol metabolic process; ureteric bud development; UV protection