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Thymus Activation Regulated Chemokine (TARC) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2003347
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MBS2003347 is an antibody targeting TARC. Also known as Polyclonal Antibody to Thymus Activation Regulated Chemokine (TARC). Reactive in Human. Host: Rabbit. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Thymus Activation Regulated Chemokine (TARC), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Thymus Activation Regulated Chemokine (TARC)
Product Gene Name
anti-TARC antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
1mg/ml (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for 24 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: TARC (MBS2003347)
Biotin Conjugated Antibody: TARC (MBS2004499)
Matching Pairs
Unconjugated Antibody: TARC (MBS2003347)
Immunogen: TARC (MBS2011018)
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OMIM
D43767 mRNA
3D Structure
ModBase 3D Structure for Q92583
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Traits
Liquid
Immunogen
Recombinant TARC (Ala24~Ser94 (Accession # Q92583)) expressed in E.coli ( MBS2011018 ).
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-TARC antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP).
Application Notes for anti-TARC antibody
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-TARC antibody

Figure. Western Blot; Sample: Recombinant TARC, Human.
Rabbit Anti-TARC Polyclonal Antibody – Cat# MBS2003347

Immunohistochemistry (IHC) of anti-TARC antibody

DABstainingonIHC-P.Samples:HumanTissue)
Rabbit Anti-TARC Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2003347

Other Notes

Small volumes of anti-TARC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TARC. It may not necessarily be applicable to this product.

NCBI GI #
4506829
NCBI GeneID
6361
NCBI Accession #
NP_002978.1
UniProt Primary Accession #
Q92583
UniProt Secondary Accession #
Q2M287; A0N0Q9
UniProt Related Accession #
Q92583
GenBank Nucleotide #
NM_002987.2
NCBI Official Full Name
C-C motif chemokine 17
NCBI Official Synonym Full Names
C-C motif chemokine ligand 17
NCBI Official Symbol
CCL17
NCBI Official Synonym Symbols
TARC; ABCD-2; SCYA17; A-152E5.3
UniProt Protein Name
C-C motif chemokine 17
UniProt Synonym Protein Names
CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine
UniProt Gene Name
CCL17
UniProt Synonym Gene Names
SCYA17; TARC
NCBI Protein Information
C-C motif chemokine 17

NCBI Summary for TARC

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014]
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UniProt Comments for TARC

CCL17: Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q21

Cellular Component: extracellular space

Molecular Function: CCR chemokine receptor binding; CCR4 chemokine receptor binding; chemokine activity; receptor binding

Biological Process: cell-cell signaling; chemotaxis; G-protein coupled receptor signaling pathway; inflammatory response; lymphocyte chemotaxis; monocyte chemotaxis; multicellular organism development; negative regulation of myoblast differentiation; neutrophil chemotaxis; positive regulation of GTPase activity
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Research Articles on TARC

1. TARC is a candidate biomarker for PTSD only in males.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TARC antibody

 Reference Product  PubMed Publications
 CCR4 antibody  >247 publications with TARC and CCR4
 CXCR3 antibody  >60 publications with TARC and CXCR3
 CCR5 antibody  >36 publications with TARC and CCR5
 CCR8 antibody  >34 publications with TARC and CCR8
 CCR3 antibody  >32 publications with TARC and CCR3
 CCR7 antibody  >23 publications with TARC and CCR7
 CCR6 antibody  >20 publications with TARC and CCR6
 STAT6 antibody  >20 publications with TARC and STAT6
 CCR1 antibody  >16 publications with TARC and CCR1
 CCR2 antibody  >12 publications with TARC and CCR2

Pathways associated with anti-TARC antibody

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 IL4-mediated Signaling Events Pathway antibodies  IL4-mediated Signaling Events Pathway Diagram

Diseases associated with anti-TARC antibody

 Disease Name  Pubmed Publications
 Hypersensitivity Antibodies  >293 publications with TARC and Hypersensitivity
 Inflammation Antibodies  >272 publications with TARC and Inflammation
 Respiratory Tract Diseases Antibodies  >184 publications with TARC and Respiratory Tract Diseases
 Dermatitis, Atopic Antibodies  >168 publications with TARC and Dermatitis, Atopic
 Lung Diseases Antibodies  >153 publications with TARC and Lung Diseases
 Asthma Antibodies  >136 publications with TARC and Asthma
 Respiratory Hypersensitivity Antibodies  >118 publications with TARC and Respiratory Hypersensitivity
 Necrosis Antibodies  >102 publications with TARC and Necrosis
 Disease Models, Animal Antibodies  >70 publications with TARC and Disease Models, Animal
 Fibrosis Antibodies  >34 publications with TARC and Fibrosis

Organs/Tissues associated with anti-TARC antibody

 Organ/Tissue Name  Pubmed Publications
 Mammary Gland Antibodies  >1 publications with TARC and Mammary Gland
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