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DECR1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200437

DECR1 is a mitochondrial protein that exists as a homotetramer and belongs to the family of short-chain dehydrogenases/reductases. It functions as an auxiliary enzyme of beta-oxidation andt participates in the metabolism of unsaturated fatty enoyl-CoA esters.… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DECR1, Monoclonal Antibody
Full Product Name
DECR1 antibody
Product Gene Name
Product Synonym Names
24-dienoyl-CoA reductase mitochondrial; 2,4-dienoyl-CoA reductase; mitochondrial; DECR; NADPH; SDR18C1
Clonality
Monoclonal
Isotype
IgG2b, k
Clone Number
AT3B2
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
Purity/Purification
By protein-A affinity chromatography
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
34,994 Da
OMIM
L26050 mRNA
3D Structure
ModBase 3D Structure for Q16698
Antigen Species
Human
Immunogen
Recombinant human DECR1 (35-335aa) purified from E. coli
Clone Note
Anti-human DECR1 mAb, clone AT3B2, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human DECR1 protein.

Product Categories/Family for anti-DECR1 antibody

Applications Tested/Suitable for anti-DECR1 antibody
ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Western Blot (WB) of anti-DECR1 antibody

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human DECR1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: PC3 cell lysate Lane 2.: HepG2 cell lysate
Mouse Anti-DECR1 Monoclonal Antibody – Cat# MBS200437

Immunofluorescence (IF) of anti-DECR1 antibody

ICC/IF analysis of DECR1 in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human DECR1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
Mouse Anti-DECR1 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS200437

Product References and Citations for anti-DECR1 antibody

Koivuranta KT., et al. (1994) Biochem J. 304 (3): 787-92.; Roe CR., et al. (1990) J Clin Invest. 85 (5): 1703-7.

Other Notes

Small volumes of anti-DECR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DECR1 purchase

MBS200437 is an antibody targeting DECR1. Also known as DECR1 antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for DECR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
2,4-dienoyl-CoA reductase, mitochondrial isoform 1
NCBI Official Synonym Full Names
2,4-dienoyl-CoA reductase 1
NCBI Official Symbol
DECR1
NCBI Official Synonym Symbols
DECR; NADPH; SDR18C1
UniProt Protein Name
2,4-dienoyl-CoA reductase, mitochondrial
UniProt Synonym Protein Names
2,4-dienoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase [NADPH]; Short chain dehydrogenase/reductase family 18C member 1
UniProt Gene Name
DECR1
UniProt Synonym Gene Names
DECR; SDR18C1; 4-enoyl-CoA reductase [NADPH]
NCBI Protein Information
2,4-dienoyl-CoA reductase, mitochondrial

NCBI Summary for DECR1

This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. [provided by RefSeq, Jul 2008]

UniProt Comments for DECR1

Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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