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FABP1/L-FABP Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200484

FABP1 (Fatty acid binding protein1) encodes the fatty acid binding protein found in liver. FABP1 is composed of ten antiparallelbeta strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acid. This… More details

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Product Overview

Online Datasheet in PDF
Product Name
FABP1/L-FABP, Monoclonal Antibody
Full Product Name
FABP1/L-FABP
Product Gene Name
anti-FABP1/L-FABP antibody
Product Synonym Names
Fatty acid binding protein 1; Fatty acid-binding protein; liver; FABPL; L-FABP; FABP1; Fatty acid binding protein 1; fatty acid binding protein 1 liver
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
2G4
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid; In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Concentration
1mg/ml (lot specific)
Preparation and Storage
Can be stored at 2 degree C to 8 degree C for 1 week. For long term storage, aliquot and store at -20 degree C to -80 degree C. Avoid repeated freezing and thawing cycles.
OMIM
134650
3D Structure
ModBase 3D Structure for P07148
Immunogen
Recombinant human FABP1/L-FABP (1-127aa) purified from E Coli.
Conjugation
Unconjugated

Product Categories/Family for anti-FABP1/L-FABP antibody

Cancer; Cardiovascular; Lysates; Metabolism; Other; Signal Transduction
Applications Tested/Suitable for anti-FABP1/L-FABP antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Immunocytochemistry/Immunofluorescence (ICC/IF) of anti-FABP1/L-FABP antibody

ICC/IF analysis of FABP1/L-FABP in Hep3B cells. The cell was stained (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
Mouse Anti-FABP1/L-FABP Monoclonal Antibody – Cat# MBS200484

Western Blot (WB) of anti-FABP1/L-FABP antibody

The Recombinant protein (50ng) and Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human FABP1/L-FABP antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.; Lane 1.: Recombinant human FABP1/L-FABP protein; Lane 2.: HepG2 cell lysate;Lane 3.: Mouse Liver tissue lysate
Mouse Anti-FABP1/L-FABP Monoclonal Antibody, Western Blot (WB) – Cat# MBS200484

Product References and Citations for anti-FABP1/L-FABP antibody

Atshaves BP, et al: (2004) Mol Cell Biochem. 259(1-2), 115-29. Nakamura T, et al: (2005) Diabestes Care. 28(11), 2728-32

Other Notes

Small volumes of anti-FABP1/L-FABP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FABP1/L-FABP purchase

MBS200484 is an antibody targeting FABP1/L-FABP. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FABP1/L-FABP. It may not necessarily be applicable to this product.

NCBI GI #
182358
NCBI GeneID
2168
NCBI Accession #
AAA52419.1
UniProt Primary Accession #
P07148
UniProt Related Accession #
P07148
NCBI Official Full Name
L-FABP
NCBI Official Synonym Full Names
fatty acid binding protein 1
NCBI Official Symbol
FABP1
NCBI Official Synonym Symbols
FABPL; L-FABP
UniProt Protein Name
Fatty acid-binding protein, liver
UniProt Synonym Protein Names
Fatty acid-binding protein 1; Liver-type fatty acid-binding protein
UniProt Gene Name
FABP1
UniProt Synonym Gene Names
FABPL; L-FABP
UniProt Entry Name
FABPL_HUMAN
NCBI Protein Information
fatty acid-binding protein, liver

NCBI Summary for FABP1/L-FABP

This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]
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UniProt Comments for FABP1/L-FABP

Function: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.

Subcellular location: Cytoplasm.

Domain: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

Sequence similarities: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
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Research Articles on FABP1/L-FABP

1. The data indicated that FABP1 impacts hepatocyte EC levels by binding EC and differentially impacts their intracellular hydrolysis (2-AG) and uptake (AEA).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FABP1/L-FABP antibody

 Reference Product  PubMed Publications
 PPARA antibody  >2 publications with FABP1/L-FABP and PPARA

Pathways associated with anti-FABP1/L-FABP antibody

 Products by Pathway  Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
 Selenium Metabolism And Selenoproteins Pathway antibodies  Selenium Metabolism And Selenoproteins Pathway Diagram

Diseases associated with anti-FABP1/L-FABP antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >293 publications with FABP1/L-FABP and Fatty Liver
 Kidney Diseases Antibodies  >58 publications with FABP1/L-FABP and Kidney Diseases
 Liver Diseases Antibodies  >57 publications with FABP1/L-FABP and Liver Diseases
 Acute Kidney Injury Antibodies  >28 publications with FABP1/L-FABP and Acute Kidney Injury
 Liver Neoplasms Antibodies  >28 publications with FABP1/L-FABP and Liver Neoplasms
 Cardiovascular Diseases Antibodies  >25 publications with FABP1/L-FABP and Cardiovascular Diseases
 Inflammation Antibodies  >17 publications with FABP1/L-FABP and Inflammation
 Carcinoma, Hepatocellular Antibodies  >12 publications with FABP1/L-FABP and Carcinoma, Hepatocellular
 Hypertension Antibodies  >11 publications with FABP1/L-FABP and Hypertension
 Necrosis Antibodies  >10 publications with FABP1/L-FABP and Necrosis

Organs/Tissues associated with anti-FABP1/L-FABP antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >301 publications with FABP1/L-FABP and Liver
 Intestine Antibodies  >93 publications with FABP1/L-FABP and Intestine
 Kidney Antibodies  >69 publications with FABP1/L-FABP and Kidney
 Muscle Antibodies  >26 publications with FABP1/L-FABP and Muscle
 Stomach Antibodies  >11 publications with FABP1/L-FABP and Stomach
 Embryonic Tissue Antibodies  >10 publications with FABP1/L-FABP and Embryonic Tissue
 Lung Antibodies  >6 publications with FABP1/L-FABP and Lung
 Placenta Antibodies  >6 publications with FABP1/L-FABP and Placenta
 Prostate Antibodies  >3 publications with FABP1/L-FABP and Prostate
 Mammary Gland Antibodies  >1 publications with FABP1/L-FABP and Mammary Gland
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