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Chorionic Gonadotropin Alpha Polypeptide (CGa) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2006519
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MBS2006519 is an antibody targeting CGa. Also known as Polyclonal Antibody to Chorionic Gonadotropin Alpha Polypeptide (CGa). Reactive in Human, Mouse. Host: Rabbit. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Chorionic Gonadotropin Alpha Polypeptide (CGa), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Chorionic Gonadotropin Alpha Polypeptide (CGa)
Product Gene Name
anti-CGa antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
1mg/ml (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: CGa (MBS2006519)
Biotin Conjugated Antibody: CGa (MBS2007034)
Matching Pairs
Unconjugated Antibody: CGa (MBS2006519)
Immunogen: CGa (MBS2011461)
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3D Structure
ModBase 3D Structure for P01216
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Traits
Liquid
Cross Reactivity
Human; Rat
Immunogen
Recombinant CGa (Leu25~Ser120) expressed in E.coli (MBS2011461).
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CGa antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP).
Application Notes for anti-CGa antibody
Western blotting: 0.5-2ug/mL;
Immunohistochemistry: 5-20ug/mL;
Immunocytochemistry: 5-20ug/mL;
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-CGa antibody

Western Blot: Sample: Recombinant CGa, Mouse.
Rabbit Anti-CGa Polyclonal Antibody – Cat# MBS2006519

Western Blot(WB) of anti-CGa antibody

Western Blot; Sample: Lane1: Mouse Cerebellum lysate;
Lane2: Human Placenta lysate
Primary Ab: 1.5ug/ml Rabbit Anti-Mouse CGa Antibody
Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Rabbit Anti-CGa Polyclonal Antibody, Western Blot(WB) – Cat# MBS2006519

Immunohistochemistry (IHC) of anti-CGa antibody

DAB staining on IHC-P; Samples: Mouse Kidney Tissue)
Rabbit Anti-CGa Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2006519

Other Notes

Small volumes of anti-CGa antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CGa. It may not necessarily be applicable to this product.

NCBI GI #
6753414
NCBI GeneID
12640
NCBI Accession #
NP_034019.1
UniProt Primary Accession #
P01216
UniProt Secondary Accession #
P11963; Q5M8P4
UniProt Related Accession #
P01216
GenBank Nucleotide #
NM_009889.2
NCBI Official Full Name
glycoprotein hormones alpha chain
NCBI Official Synonym Full Names
glycoprotein hormones, alpha subunit
NCBI Official Symbol
Cga
NCBI Official Synonym Symbols
HCG; LHA; FSHA; Tsha; aGSU; GPHA1; alphaSU; CG-alpha; GPHalpha; alphaGSU; alpha-GSU
UniProt Protein Name
Glycoprotein hormones alpha chain
UniProt Synonym Protein Names
Anterior pituitary glycoprotein hormones common subunit alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain
Protein Family
Glycoprotein hormones
UniProt Gene Name
Cga
UniProt Synonym Gene Names
FSH-alpha; LSH-alpha; TSH-alpha
NCBI Protein Information
glycoprotein hormones alpha chain

UniProt Comments for CGa

CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4 A5|4 16.86 cM

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: cellular response to hormone stimulus; developmental growth; follicle-stimulating hormone secretion; gonad development; luteinizing hormone secretion; negative regulation of organ growth; thyroid gland development; thyroid hormone generation
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Research Articles on CGa

1. TSH improves insulin sensitivity in skeletal muscle by increasing Irs1 gene expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CGa antibody

 Reference Product  PubMed Publications
 Lhb antibody  >28 publications with CGa and Lhb
 Fshb antibody  >27 publications with CGa and Fshb
 Pomc antibody  >19 publications with CGa and Pomc
 Inha antibody  >9 publications with CGa and Inha
 Fshr antibody  >6 publications with CGa and Fshr
 Tshb antibody  >5 publications with CGa and Tshb
 Lhcgr antibody  >3 publications with CGa and Lhcgr
 Inhbb antibody  >1 publications with CGa and Inhbb
 Inhba antibody  >1 publications with CGa and Inhba

Pathways associated with anti-CGa antibody

 Products by Pathway  Pathway Diagram
 Amine-derived Hormones Pathway antibodies  Amine-derived Hormones Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram

Diseases associated with anti-CGa antibody

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >280 publications with CGa and Adenocarcinoma
 Nervous System Diseases Antibodies  >170 publications with CGa and Nervous System Diseases
 Prostatic Neoplasms Antibodies  >137 publications with CGa and Prostatic Neoplasms
 Lung Neoplasms Antibodies  >116 publications with CGa and Lung Neoplasms
 Cardiovascular Diseases Antibodies  >108 publications with CGa and Cardiovascular Diseases
 Disease Progression Antibodies  >95 publications with CGa and Disease Progression
 Hyperplasia Antibodies  >77 publications with CGa and Hyperplasia
 Liver Diseases Antibodies  >68 publications with CGa and Liver Diseases
 Liver Neoplasms Antibodies  >68 publications with CGa and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >67 publications with CGa and Neoplasm Metastasis

Organs/Tissues associated with anti-CGa antibody

 Organ/Tissue Name  Pubmed Publications
 Pituitary Gland Antibodies  >73 publications with CGa and Pituitary Gland
 Embryonic Tissue Antibodies  >22 publications with CGa and Embryonic Tissue
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