Glial Fibrillary Acidic Protein (GFAP) Antibody – Rabbit Polyclonal

GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 10q32.1

Cellular Component: cell projection; cytoplasm; intermediate filament; intermediate filament cytoskeleton; intracellular; membrane; myelin sheath

Molecular Function: identical protein binding; integrin binding; kinase binding; protein binding; structural constituent of cytoskeleton; structural molecule activity

Biological Process: astrocyte development; Bergmann glial cell differentiation; extracellular matrix organization; intermediate filament organization; intermediate filament-based process; neuron projection regeneration; regulation of neurotransmitter uptake; response to wounding