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Interleukin 18 Receptor Accessory Protein (IL18RAP) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2006814
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MBS2006814 is an antibody targeting IL18RAP. Also known as Polyclonal Antibody to Interleukin 18 Receptor Accessory Protein (IL18RAP). Reactive in Mouse, Rat. Host: Rabbit. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interleukin 18 Receptor Accessory Protein (IL18RAP), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Interleukin 18 Receptor Accessory Protein (IL18RAP)
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
1mg/ml (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: IL18RAP (MBS2006814)
Biotin Conjugated Antibody: IL18RAP (MBS2001683)
Matching Pairs
Unconjugated Antibody: IL18RAP (MBS2006814)
Immunogen: IL18RAP (MBS2009868)
3D Structure
ModBase 3D Structure for Q9Z2B1
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Cross Reactivity
Rat
Traits
Liquid
Immunogen
Recombinant IL18R Beta (Asn396~Ser548 (Accession # Q9Z2B1)) expressed in E.coli ( MBS2009868 ).
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-IL18RAP antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP).
Application Notes for anti-IL18RAP antibody
Western blotting: 0.5-3ug/mL
Immunohistochemistry: 5-30ug/mL
Immunocytochemistry: 5-30ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-IL18RAP antibody

Western Blot:
Sample: Recombinant IL8R Beta, Mouse.
Rabbit Anti-IL18RAP Polyclonal Antibody – Cat# MBS2006814

Western Blot (WB) of anti-IL18RAP antibody

Western Blot:
Sample: Mouse Serum;
Primary Ab: 2ug/ml Rabbit Anti-Mouse IL18RAP Antibody
Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047)
Rabbit Anti-IL18RAP Polyclonal Antibody, Western Blot (WB) – Cat# MBS2006814

Immunohistochemistry (IHC) of anti-IL18RAP antibody

DAB staining on IHC-P;
Samples: Mouse Stomach Tissue;
Primary Ab: 30ug/ml Rabbit Anti-Mouse IL18RAP Antibody
Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 )
Rabbit Anti-IL18RAP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2006814

Immunohistochemistry (IHC) of anti-IL18RAP antibody

DAB staining on fromalin fixed paraffin- embedded liver tissue)
Rabbit Anti-IL18RAP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2006814

Immunohistochemistry (IHC) of anti-IL18RAP antibody

DAB staining on IHC-P;
Samples: Mouse Uterus Tissue)
Rabbit Anti-IL18RAP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2006814

Other Notes

Small volumes of anti-IL18RAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL18RAP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-18 receptor accessory protein
NCBI Official Synonym Full Names
interleukin 18 receptor accessory protein
NCBI Official Symbol
Il18rap
NCBI Official Synonym Symbols
AcPL; IL-18RAcP; IL-1RAcPL; IL-18Rbeta; IL-18R-beta
UniProt Protein Name
Interleukin-18 receptor accessory protein
UniProt Synonym Protein Names
Accessory protein-like; AcPL; CD218 antigen-like family member B; IL-1R accessory protein-like; IL-1RAcPL; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta; IL-18R-beta; IL-18Rbeta; CD_antigen: CD218b
UniProt Gene Name
Il18rap
UniProt Synonym Gene Names
IL-18 receptor accessory protein; IL-18RAcP; AcPL; IL-1RAcPL; IL-18R-beta; IL-18Rbeta
NCBI Protein Information
interleukin-18 receptor accessory protein

NCBI Summary for IL18RAP

Interleukin-18 (or interferon-gamma inducing factor) is a proinflammatory cytokine that induces cell-mediated immunity following microbial infection. This gene encodes a member of the interleukin-1 receptor family. The encoded protein is an accessory subunit of the receptor for interleukin-18 and mediates signaling through this cytokine. Mice lacking this gene exhibit a defective cell-mediated immune response. [provided by RefSeq, Jan 2014]
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UniProt Comments for IL18RAP

IL18RAP: Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex. Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK. Belongs to the interleukin-1 receptor family.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1|1 B

Cellular Component: integral component of membrane; membrane

Molecular Function: interleukin-1 receptor activity

Biological Process: cell proliferation; interferon-gamma production; interleukin-6 production; neutrophil activation; positive regulation of natural killer cell mediated cytotoxicity; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-IL18RAP antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >1 publications with IL18RAP and Skin
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