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Interferon Alpha (IFNa) Antibody – Guinea Pig Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2006910
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MBS2006910 is an antibody targeting IFNa. Also known as Polyclonal Antibody to Interferon Alpha (IFNa). Reactive in Rabbit. Host: Guinea Pig. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interferon Alpha (IFNa), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Interferon Alpha (IFNa)
Product Gene Name
anti-IFNa antibody
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF -SCLKDRKDF G FPLEKVDAQQ IQKAQAISIL HELSQQVLNI YTSXDSSAAW DATLLDSFCN DLQQQLSGLQ ACQMHQVGVQ EPPLAQEDSL LAV
Clonality
Polyclonal
Isotype
IgG
Host
Guinea Pig
Species Reactivity
Rabbit
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
200ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against IFNa. It has been selected for its ability to recognize IFNa in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Molecular Weight
22,319 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (21140631..21142144, complement). Location: 9p22
OMIM
147553
3D Structure
ModBase 3D Structure for P05000
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant IFNa (Ser1~Val93) expressed in E.coli.
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-IFNa antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-IFNa antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-IFNa antibody

WB Image
Guinea Pig Anti-IFNa Polyclonal Antibody – Cat# MBS2006910

Other Notes

Small volumes of anti-IFNa antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IFNa. It may not necessarily be applicable to this product.

NCBI GI #
386800
NCBI GeneID
3467
NCBI Accession #
AAA52724.1
UniProt Primary Accession #
P05000
UniProt Secondary Accession #
Q13168; Q5U802; Q5VWD0; Q7M4P5
UniProt Related Accession #
P05000
NCBI Official Full Name
interferon-alpha
NCBI Official Synonym Full Names
interferon, omega 1
NCBI Official Symbol
IFNW1
UniProt Protein Name
Interferon omega-1
UniProt Synonym Protein Names
Interferon alpha-II-1
UniProt Gene Name
IFNW1
UniProt Entry Name
IFNW1_HUMAN
NCBI Protein Information
interferon omega-1; interferon alpha-II-1; IFN-omega 1, interferon omega-1

UniProt Comments for IFNa

IFNW1: Belongs to the alpha/beta interferon family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: extracellular space

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding; cytokine activity

Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; response to virus; regulation of MHC class I biosynthetic process; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; B cell differentiation; natural killer cell activation during immune response; innate immune response; cell cycle arrest; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein
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Research Articles on IFNa

1. Studies indicate that upregulation of the type I interferon protein signature has added additional markers of disease activity and insight into the pathogenesis of the disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IFNa antibody

 Reference Product  PubMed Publications
 IFNA2 antibody  >1 publications with IFNa and IFNA2
 MTAP antibody  >1 publications with IFNa and MTAP

Pathways associated with anti-IFNa antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 RIG-I-like Receptor Signaling Pathway antibodies  RIG-I-like Receptor Signaling Pathway Diagram
 RIG-I-like Receptor Signaling Pathway antibodies  RIG-I-like Receptor Signaling Pathway Diagram

Diseases associated with anti-IFNa antibody

 Disease Name  Pubmed Publications
 Skin Neoplasms Antibodies  >1 publications with IFNa and Skin Neoplasms
 Immune System Diseases Antibodies  >1 publications with IFNa and Immune System Diseases
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