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CD72 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS201134

CD72, also known as B-cell differentiation antigen CD72, is a type II transmembrane glycoprotein carrying a C-type lectin domain. It plays a role in immune system regulation of animals and expressed on B lineage cells, NK cells, monocytes, dendritic cells,… More details

$265 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD72, Recombinant Protein
Full Product Name
Recombinant CD72
Product Gene Name
CD72 recombinant protein
Product Synonym Names
CD72; CD72b; LYB2; B-cell differentiation antigen CD72; Lyb-2; CD_antigen: CD72
Sequence
ADP RYLQVSQ QLQQTNRVLE VTNSSLRQQL RLKITQLGQS AEDLQGSRRE LAQSQEALQV EQRAHQAAEG QLQACQADRQ KTKETLQSEE QQRRALEQKL SNMENRLKPF FTCGSADTCC PSGWIMHQKS CFYISLTSKN WQESQKQCET LSSKLATFSE IYPQSHSYYF LNSLLPNGGS GNSYWTGLSS NKDWKLTDDT QRTRTYAQSS KCNKVHKTWS WWTLESESCR SSLPYICEMT AFRFPD LEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH
Host
Baculovirus
Form/Format
Liquid; In 50mM Tris-HCl (pH 6.8) Containing 2mM DTT, 0.2M NaCl, 50% Glycerol.
Purity/Purification
>90% by SDS-PAGE
Concentration
0.5mg/ml (determined by Absorbance at 280nm) (lot specific)
Preparation and Storage
Can be stored at 2 degree C to 8 degree C for 1 week. For long term storage, aliquot and store at -20 degree C to -80 degree C. Avoid repeated freezing and thawing cycles.
Molecular Weight
55.3kDa (485aa); 50-70kDa (SDS-PAGE under reducing conditions)
Sequence Positions
117-359aa
OMIM
107272
3D Structure
ModBase 3D Structure for P21854
Species
Human
Endotoxin
<1 EU per 1ug of protein (determined by LAL method)
Tag
hIgG-His-Tag
Predicted N-Terminal
Ala

Product Categories/Family for CD72 recombinant protein

Immunology
Applications Tested/Suitable for CD72 recombinant protein
SDS-PAGE

SDS-Page of CD72 recombinant protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain
CD72 Recombinant Protein – Cat# MBS201134

Product References and Citations for CD72 recombinant protein

Vadasz Z., et al, (2014) Semin. Arthritis Rheum. 43:767-771. Adachi T., et al, (1998) J. Immunol. 160:4662-4665.

Other Notes

Small volumes of CD72 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD72 purchase

MBS201134 is a recombinant protein targeting CD72. Also known as Recombinant CD72. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for CD72. It may not necessarily be applicable to this product.

NCBI GI #
4502683
NCBI GeneID
971
NCBI Accession #
NP_001773.1
UniProt Primary Accession #
P21854
UniProt Related Accession #
P21854
GenBank Nucleotide #
NP_001773.1
NCBI Official Full Name
B-cell differentiation antigen CD72
NCBI Official Synonym Full Names
CD72 molecule
NCBI Official Symbol
CD72
NCBI Official Synonym Symbols
LYB2; CD72b
UniProt Protein Name
B-cell differentiation antigen CD72
UniProt Synonym Protein Names
Lyb-2; CD_antigen: CD72
Protein Family
B-cell differentiation antigen
UniProt Gene Name
CD72
UniProt Entry Name
CD72_HUMAN
NCBI Protein Information
B-cell differentiation antigen CD72

UniProt Comments for CD72

CD72: Plays a role in B-cell proliferation and differentiation.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9p13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: protein binding; transmembrane receptor activity; carbohydrate binding; receptor binding

Biological Process: axon guidance; signal transduction; cell adhesion
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Research Articles on CD72

1. Interferon-alpha-induced CD100 expression on naive CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CD72 recombinant protein

 Reference Product  PubMed Publications
 CD5 recombinant protein  >53 publications with CD72 and CD5
 SEMA4D recombinant protein  >36 publications with CD72 and SEMA4D
 PTPN6 recombinant protein  >10 publications with CD72 and PTPN6
 CD79B recombinant protein  >5 publications with CD72 and CD79B
 SYK recombinant protein  >5 publications with CD72 and SYK
 LYN recombinant protein  >5 publications with CD72 and LYN
 BTK recombinant protein  >4 publications with CD72 and BTK
 CD79A recombinant protein  >2 publications with CD72 and CD79A
 BLNK recombinant protein  >1 publications with CD72 and BLNK

Pathways associated with CD72 recombinant protein

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Other Semaphorin Interactions Pathway antibodies  Other Semaphorin Interactions Pathway Diagram
 Semaphorin Interactions Pathway antibodies  Semaphorin Interactions Pathway Diagram

Diseases associated with CD72 recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >12 publications with CD72 and Inflammation
 Respiratory Tract Diseases Antibodies  >8 publications with CD72 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >7 publications with CD72 and Lung Diseases
 Kidney Diseases Antibodies  >7 publications with CD72 and Kidney Diseases
 Necrosis Antibodies  >7 publications with CD72 and Necrosis
 Neoplasms, Experimental Antibodies  >5 publications with CD72 and Neoplasms, Experimental
 Pneumonia Antibodies  >3 publications with CD72 and Pneumonia
 Dermatitis, Atopic Antibodies  >2 publications with CD72 and Dermatitis, Atopic
 Diabetes Mellitus Antibodies  >2 publications with CD72 and Diabetes Mellitus
 Breast Neoplasms Antibodies  >2 publications with CD72 and Breast Neoplasms

Organs/Tissues associated with CD72 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >172 publications with CD72 and Blood
 Spleen Antibodies  >21 publications with CD72 and Spleen
 Lung Antibodies  >10 publications with CD72 and Lung
 Kidney Antibodies  >5 publications with CD72 and Kidney
 Lymph Node Antibodies  >5 publications with CD72 and Lymph Node
 Lymph Antibodies  >5 publications with CD72 and Lymph
 Tonsil Antibodies  >4 publications with CD72 and Tonsil
 Skin Antibodies  >4 publications with CD72 and Skin
 Intestine Antibodies  >4 publications with CD72 and Intestine
 Thymus Antibodies  >4 publications with CD72 and Thymus
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