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CD8 alpha Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS201166

CD8 alpha, also known as T-cell surface glycoprotein CD8 alpha chain isoform 1, is a member of integralmembrane glycoprotein that plays an essential role in the immune response and serves multiple functions inresponses. It interacts with the T-cell receptor… More details

$250 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD8 alpha, Recombinant Protein
Full Product Name
Recombinant CD8 alpha
Product Synonym Names
CD8A; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD8a; MAL; CD8; Leu2; p32; T-cell surface glycoprotein CD8 alpha chain isoform 1
Sequence
SQFRV SP LDRTWNLGET VELKCQVLLS NPTSGCSWLF QPRGAAASPT FLLYLSQNKP KAAEGLDTQR FSGKRLGDTF VLTLSDFRRE NEGYYFCSAL SNSIMYFSHF VPVFLPAKPT TTPAPRPPTP APTIASQPLS LRPEACRPAA GGAVHTRGLD FACD
Host
Baculovirus
Form/Format
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.
Purity/Purification
> 95% by SDS - PAGE
Concentration
0.5mg/ml (determined by Absorbance at 280nm) (lot specific)
Preparation and Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
18.7kDa (170aa)
Sequence Positions
22-182aa
OMIM
186910
3D Structure
ModBase 3D Structure for P01732
Tag
His-Tag
Predicted nterm
Ala
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)

Product Categories/Family for CD8 alpha recombinant protein

Applications Tested/Suitable for CD8 alpha recombinant protein
SDS-PAGE

SDS-Page of CD8 alpha recombinant protein

3ug by SDS-PAGE under reducing condition andvisualized by coomassie blue stain
CD8 alpha Recombinant Protein – Cat# MBS201166

Product References and Citations for CD8 alpha recombinant protein

Harland KL., et al. (2014) Nat Commun. 5:3547.;; Chen S., et al. (2019) J Cancer. 10:697-707.

Other Notes

Small volumes of CD8 alpha recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD8 alpha purchase

MBS201166 is a recombinant protein targeting CD8 alpha. Also known as Recombinant CD8 alpha. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for CD8 alpha. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
T-cell surface glycoprotein CD8 alpha chain isoform 1
NCBI Official Synonym Full Names
CD8a molecule
NCBI Official Symbol
CD8A
NCBI Official Synonym Symbols
CD8; p32; Leu2
UniProt Protein Name
T-cell surface glycoprotein CD8 alpha chain
UniProt Synonym Protein Names
T-lymphocyte differentiation antigen T8/Leu-2
UniProt Gene Name
CD8A
UniProt Synonym Gene Names
MAL
UniProt Entry Name
CD8A_HUMAN
NCBI Protein Information
T-cell surface glycoprotein CD8 alpha chain

NCBI Summary for CD8 alpha

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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