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LRIG1 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS201238

LRIG1, also known as leucine-rich repeats and immunoglobulin-like domains 1 is a pan-negative regulator of the epidermal growth factor receptor (EGFR) signaling pathway. In studies with ErbB family members and Met kinase, LRIG regulates signaling by… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LRIG1, Recombinant Protein
Full Product Name
Recombinant mouse LRIG1 protein
Product Gene Name
LRIG1 recombinant protein
Product Synonym Names
LIG-1; LIG1; leucine-rich repeats and immunoglobulin like domains 1; leucine rich repeats and immunoglobulin like domains 1; D6Bwg0781e; Img
Sequence
AQAGPRAPCA AACTCAGDSL DCSGRGLATL PRDLPSWTRS LNLSYNRLSE IDSAAFEDLT NLQEVYLNSN ELTAIPSLGA ASIGVVSLFL QHNKILSVDG SQLKSYLSLE VLDLSSNNIT EIRSSCFPNG LRIRELNLAS NRISILESGA FDGLSRSLLT LRLSKNRITQ LPVKAFKLPR LTQLDLNRNR IRLIEGLTFQ GLDSLEVLRL QRNNISRLTD GAFWGLSKMH VLHLEYNSLV EVNSGSLYGL TALHQLHLSN NSISRIQRDG WSFCQKLHEL ILSFNNLTRL DEESLAELSS LSILRLSHNA ISHIAEGAFK GLKSLRVLDL DHNEISGTIE DTSGAFTGLD NLSKLTLFGN KIKSVAKRAF SGLESLEHLN LGENAIRSVQ FDAFAKMKNL KELYISSESF LCDCQLKWLP PWLMGRMLQA FVTATCAHPE SLKGQSIFSV LPDSFVCDDF PKPQIITQPE TTMAVVGKDI RFTCSAASSS SSPMTFAWKK DNEVLANADM ENFAHVRAQD GEVMEYTTIL HLRHVTFGHE GRYQCIITNH FGSTYSHKAR LTVNVLPSFT KIPHDIAIRT GTTARLECAA TGHPNPQIAW QKDGGTDFPA ARERRMHVMP DDDVFFITDV KIDDMGVYSC TAQNSAGSVS ANATLTVLET PSLAVPLEDR VVTVGETVAF QCKATGSPTP RITWLKGGRP LSLTERHHFT PGNQLLVVQN VMIDDAGRYT CEMSNPLGTE RAHSQLSILP TPGCRKDGTT VG
Host
Baculovirus
Form/Format
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Purity/Purification
> 90% by SDS - PAGE
Concentration
0.5mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
84.8kDa (770aa)
Sequence Positions
35-796aa
3D Structure
ModBase 3D Structure for P70193
Antigen Species
Mouse
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Tag Information
His-Tag

Product Categories/Family for LRIG1 recombinant protein

Cancer
Applications Tested/Suitable for LRIG1 recombinant protein
SDS-PAGE

SDS-Page of LRIG1 recombinant protein

SDS-Page
LRIG1 Recombinant Protein – Cat# MBS201238

Product References and Citations for LRIG1 recombinant protein

JonasNilsson., et al, (2001) Biochem Biophys Res Commun. 284:1155–1161.;; Gal Gur., et al, (2004) EMBO J. 23:3270–3281.;; Xi Zhang., et al, (2015) Cell Stress Chaperones. 20:631-641.

Other Notes

Small volumes of LRIG1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LRIG1 purchase

MBS201238 is a recombinant protein targeting LRIG1. Also known as Recombinant mouse LRIG1 protein. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for LRIG1. It may not necessarily be applicable to this product.

NCBI GI #
88014689
NCBI GeneID
16206
NCBI Accession #
NP_032403
UniProt Primary Accession #
P70193
UniProt Related Accession #
P70193
GenBank Nucleotide #
NP_032403.2
NCBI Official Full Name
leucine-rich repeats and immunoglobulin-like domains protein 1 isoform 1
NCBI Official Synonym Full Names
leucine-rich repeats and immunoglobulin-like domains 1
NCBI Official Symbol
Lrig1
NCBI Official Synonym Symbols
Img; LIG-1; D6Bwg0781e
UniProt Protein Name
Leucine-rich repeats and immunoglobulin-like domains protein 1
Protein Family
Leucine-rich repeats and immunoglobulin-like domains protein
UniProt Gene Name
Lrig1
UniProt Synonym Gene Names
LIG-1
UniProt Entry Name
LRIG1_MOUSE
NCBI Protein Information
leucine-rich repeats and immunoglobulin-like domains protein 1

Research Articles on LRIG1

1. Lrig1 is expressed primarily by differentiated cells, but that these cells can be recruited to contribute to the maintenance of the gastric epithelium.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with LRIG1 recombinant protein

 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By EGFR Pathway antibodies  Signaling By EGFR Pathway Diagram
 Signaling By EGFR In Cancer Pathway antibodies  Signaling By EGFR In Cancer Pathway Diagram

Diseases associated with LRIG1 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >43 publications with LRIG1 and Neoplasms
 Carcinoma Antibodies  >16 publications with LRIG1 and Carcinoma
 Breast Neoplasms Antibodies  >8 publications with LRIG1 and Breast Neoplasms
 Nervous System Diseases Antibodies  >8 publications with LRIG1 and Nervous System Diseases
 Carcinoma, Squamous Cell Antibodies  >7 publications with LRIG1 and Carcinoma, Squamous Cell
 Adenocarcinoma Antibodies  >5 publications with LRIG1 and Adenocarcinoma
 Urinary Bladder Neoplasms Antibodies  >4 publications with LRIG1 and Urinary Bladder Neoplasms
 Skin Neoplasms Antibodies  >4 publications with LRIG1 and Skin Neoplasms
 Kidney Neoplasms Antibodies  >4 publications with LRIG1 and Kidney Neoplasms
 Uterine Cervical Neoplasms Antibodies  >4 publications with LRIG1 and Uterine Cervical Neoplasms

Organs/Tissues associated with LRIG1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >19 publications with LRIG1 and Skin
 Brain Antibodies  >11 publications with LRIG1 and Brain
 Intestine Antibodies  >5 publications with LRIG1 and Intestine
 Bladder Antibodies  >4 publications with LRIG1 and Bladder
 Lung Antibodies  >3 publications with LRIG1 and Lung
 Stomach Antibodies  >2 publications with LRIG1 and Stomach
 Muscle Antibodies  >2 publications with LRIG1 and Muscle
 Bone Antibodies  >1 publications with LRIG1 and Bone
 Liver Antibodies  >1 publications with LRIG1 and Liver
 Tongue Antibodies  >1 publications with LRIG1 and Tongue
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