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Programmed Cell Death Protein 1 Ligand 2 (PDCD1LG2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2014874
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2014874 is an antibody targeting PDCD1LG2. Also known as Polyclonal Antibody to Programmed Cell Death Protein 1 Ligand 2 (PDCD1LG2). Reactive in Rat. Host: Rabbit. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Programmed Cell Death Protein 1 Ligand 2 (PDCD1LG2), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Programmed Cell Death Protein 1 Ligand 2 (PDCD1LG2)
Product Gene Name
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- FTVTAPKEVY TVDFGSSVSL ECDFDRRECT ELEGIRASLQ KVENDTSSQS QRATLLEELL PLGKASFHIP SVQVRDSGQY RCLVICGAAW DYKYLTVKVK ASYVRIDTGI LEVPGTGEVQ LICQARGYPL AEVSWQNVSV PANTSHIRTP EGLYQVTSVL RLKPQPNRNF SCMFWNAHMK ELTSAIIDPL SWMEPKVPRT
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against PDCD1LG2. It has been selected for its ability to recognize PDCD1LG2 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: PDCD1LG2 (MBS2014874)
Immunogen: PDCD1LG2 (MBS2018280)
Matching Pairs
Unconjugated Antibody: PDCD1LG2 (MBS2014874)
APC-CY7 Conjugated Antibody: PDCD1LG2 (MBS2047486)
Molecular Weight
30,000 Da
3D Structure
ModBase 3D Structure for D4AAV6
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant PDCD1LG2 (Phe21~Gln268) expressed in E.coli.
Cross Reactivity
Rat
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2047488
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PDCD1LG2 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-PDCD1LG2 antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-PDCD1LG2 antibody

Western Blot: Sample: Rat Spleen lysate; Primary Ab: 2ug/ml Rabbit Anti-Rat PDCD1LG2 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Rabbit Anti-PDCD1LG2 Polyclonal Antibody – Cat# MBS2014874

Western Blot (WB) of anti-PDCD1LG2 antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-PDCD1LG2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS2014874

Immunohistochemistry (IHC) of anti-PDCD1LG2 antibody

DAB staining on IHC-P; Samples: Rat Pancreas Tissue)
Rabbit Anti-PDCD1LG2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2014874

Other Notes

Small volumes of anti-PDCD1LG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PDCD1LG2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
GenBank Nucleotide #
NCBI Official Full Name
programmed cell death 1 ligand 2
NCBI Official Synonym Full Names
programmed cell death 1 ligand 2
NCBI Official Symbol
Pdcd1lg2
UniProt Protein Name
Programmed cell death 1 ligand 2
UniProt Synonym Protein Names
Programmed cell death 1 ligand 2
Protein Family
UniProt Gene Name
Pdcd1lg2
NCBI Protein Information
programmed cell death 1 ligand 2

NCBI Summary for PDCD1LG2

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
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UniProt Comments for PDCD1LG2

PDCD1: a single-pass type I membrane protein. A negative regulator of activated T cells, is upregulated in human and mouse 'exhausted' T cells during persistent viral infection. A marker of angioimmunoblastic T-cell lymphoma and germinal center associated T cells.

Protein type: Membrane protein, integral; Apoptosis

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: protein binding; signal transducer activity

Biological Process: apoptosis; multicellular organismal development; T cell costimulation; signal transduction; humoral immune response

Disease: Systemic Lupus Erythematosus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-PDCD1LG2 antibody

 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >5 publications with PDCD1LG2 and Mixed
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