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Cyclophilin D (CYPD) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2016330
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2016330 is an antibody targeting CYPD. Also known as Polyclonal Antibody to Cyclophilin D (CYPD). Reactive in Mouse, Human, Rat. Host: Rabbit. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cyclophilin D (CYPD), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Cyclophilin D (CYPD)
Product Gene Name
anti-CYPD antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Human, Rat
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
0.24mg/ml (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: CYPD (MBS2016330)
Immunogen: CYPD (MBS2018468)
Matching Pairs
Unconjugated Antibody: CYPD (MBS2016330)
APC-CY7 Conjugated Antibody: CYPD (MBS2056222)
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3D Structure
ModBase 3D Structure for Q9CR16
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Traits
Liquid
Cross Reactivity
Human; Rat
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CYPD antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP);!!Recombinant CYP-40 (Lys9MBS2018468Asp189) expressed in E.coli (MBS2018468).
Application Notes for anti-CYPD antibody
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-CYPD antibody

Western Blot: Sample: Lane1: Mouse Serum; Lane2: Human A549 Cells; Lane3: Mouse Spleen Tissue; Lane4: Mouse Heart Tissue; Lane5: Rat Heart Tissue.
Rabbit Anti-CYPD Polyclonal Antibody – Cat# MBS2016330

Western Blot (WB) of anti-CYPD antibody

Western Blot: Sample: Recombinant CYPD, Mouse.
Rabbit Anti-CYPD Polyclonal Antibody, Western Blot (WB) – Cat# MBS2016330

Immunohistochemistry (IHC) of anti-CYPD antibody

DAB staining on fromalin fixed paraffin-embedded Bowels tissue)
Rabbit Anti-CYPD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2016330

Immunohistochemistry (IHC) of anti-CYPD antibody

DAB staining on IHC-P; Samples: Mouse Uterus Tissue)
Rabbit Anti-CYPD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2016330

Other Notes

Small volumes of anti-CYPD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CYPD. It may not necessarily be applicable to this product.

NCBI GI #
13385854
NCBI GeneID
67738
NCBI Accession #
NP_080628.1
UniProt Primary Accession #
Q9CR16
UniProt Secondary Accession #
Q543G1
UniProt Related Accession #
Q9CR16
GenBank Nucleotide #
NM_026352.4
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase D isoform 1
NCBI Official Synonym Full Names
peptidylprolyl isomerase D (cyclophilin D)
NCBI Official Symbol
Ppid
NCBI Official Synonym Symbols
Ppif; Ppidl; CYP-40; 4930564J03Rik
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase D
UniProt Synonym Protein Names
40 kDa peptidyl-prolyl cis-trans isomerase; Cyclophilin-40; CYP-40; Rotamase D
Protein Family
Bifunctional cytochrome P450/NADPH--P450 reductase
UniProt Gene Name
Ppid
UniProt Synonym Gene Names
PPIase D; CYP-40
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase D

UniProt Comments for CYPD

PPID: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.

Protein type: EC 5.2.1.8; Isomerase; Nucleolus

Chromosomal Location of Human Ortholog: 3|3 E3

Cellular Component: cytoplasm; cytosol; mitochondrion; nucleolus; nucleus

Molecular Function: cyclosporin A binding; enzyme binding; FK506 binding; heat shock protein binding; Hsp90 protein binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; transcription factor binding

Biological Process: apoptosis; negative regulation of transcription from RNA polymerase II promoter; positive regulation of apoptosis; positive regulation of protein secretion; positive regulation of viral genome replication; protein complex assembly; protein folding; protein peptidyl-prolyl isomerization; protein transport; regulation of apoptosis; transport
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Research Articles on CYPD

1. Murine eosinophil necrosis is regulated in vitro and in vivo by cyclophilin D.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-CYPD antibody

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >24 publications with CYPD and Brain Diseases
 Disease Models, Animal Antibodies  >6 publications with CYPD and Disease Models, Animal
 Pain Antibodies  >3 publications with CYPD and Pain
 Hyperplasia Antibodies  >3 publications with CYPD and Hyperplasia
 Necrosis Antibodies  >3 publications with CYPD and Necrosis
 Inflammation Antibodies  >2 publications with CYPD and Inflammation
 Pregnancy Complications Antibodies  >1 publications with CYPD and Pregnancy Complications
 Nerve Degeneration Antibodies  >1 publications with CYPD and Nerve Degeneration
 Adenocarcinoma Antibodies  >1 publications with CYPD and Adenocarcinoma
 Vascular Diseases Antibodies  >1 publications with CYPD and Vascular Diseases

Organs/Tissues associated with anti-CYPD antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >26 publications with CYPD and Brain
 Blood Antibodies  >22 publications with CYPD and Blood
 Pituitary Gland Antibodies  >22 publications with CYPD and Pituitary Gland
 Muscle Antibodies  >3 publications with CYPD and Muscle
 Liver Antibodies  >2 publications with CYPD and Liver
 Heart Antibodies  >2 publications with CYPD and Heart
 Bone Antibodies  >2 publications with CYPD and Bone
 Connective Tissue Antibodies  >1 publications with CYPD and Connective Tissue
 Lung Antibodies  >1 publications with CYPD and Lung
 Pancreas Antibodies  >1 publications with CYPD and Pancreas
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