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Protein Kinase Inhibitor Alpha (PKIa) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2016342
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MBS2016342 is an antibody targeting PKIa. Also known as Polyclonal Antibody to Protein Kinase Inhibitor Alpha (PKIa). Reactive in Homo sapiens (Human). Host: Rabbit. More details

$205 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Protein Kinase Inhibitor Alpha (PKIa), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Protein Kinase Inhibitor Alpha (PKIa)
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Homo sapiens (Human)
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
0.5mg/mL (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: PKIa (MBS2016342)
Immunogen: PKIa (MBS2018532)
Matching Pairs
Unconjugated Antibody: PKIa (MBS2016342)
APC-CY7 Conjugated Antibody: PKIa (MBS2041298)
OMIM
S76965 mRNA
3D Structure
ModBase 3D Structure for P61925
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Traits
Liquid
Cross Reactivity
Mouse; Rat
Immunogen
Recombinant PKIa (Ala13~Ala71) expressed in E.coli (MBS2018532).
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PKIa antibody
Western Blot (WB)
Application Notes for anti-PKIa antibody
Western blotting: 0.01-2ug/mL;
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-PKIa antibody

Western Blot;
Sample: Recombinant PKIa, Human.
Rabbit Anti-PKIa Polyclonal Antibody – Cat# MBS2016342

Other Notes

Small volumes of anti-PKIa antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PKIa. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cAMP-dependent protein kinase inhibitor alpha
NCBI Official Synonym Full Names
cAMP-dependent protein kinase inhibitor alpha
NCBI Official Symbol
PKIA
NCBI Official Synonym Symbols
PRKACN1
UniProt Protein Name
cAMP-dependent protein kinase inhibitor alpha
UniProt Synonym Protein Names
cAMP-dependent protein kinase inhibitor, muscle/brain isoform
UniProt Gene Name
PKIA
UniProt Synonym Gene Names
PRKACN1; PKI-alpha
NCBI Protein Information
cAMP-dependent protein kinase inhibitor alpha

NCBI Summary for PKIa

The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
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UniProt Comments for PKIa

PKIA: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family.

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 8q21.13

Cellular Component: cytoplasm; nucleus

Molecular Function: cAMP-dependent protein kinase inhibitor activity; protein binding

Biological Process: negative regulation of cAMP-dependent protein kinase activity; negative regulation of protein import into nucleus; negative regulation of transcription from RNA polymerase II promoter; regulation of G2/M transition of mitotic cell cycle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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