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Interleukin 20 Receptor Beta (IL20Rb) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2017184
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2017184 is an antibody targeting IL20Rb. Also known as Polyclonal Antibody to Interleukin 20 Receptor Beta (IL20Rb). Reactive in Human. Host: Rabbit. More details

$215 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interleukin 20 Receptor Beta (IL20Rb), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Interleukin 20 Receptor Beta (IL20Rb)
Product Gene Name
anti-IL20Rb antibody
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- APQN LSVLSTNMKH LLMWSPVIAP GETVYYSVEY QGEYESLYTS HIWIPSSWCS LTEGPECDVT DDITATVPYN LRVRATLGSQ TSAWSILKHP FNRNSTILTR PGMEITKDGF HLVIELEDLG PQFEFLVAYW RREPGAEEHV KMVRSGGIPV HLETMEPGAA YCVKAQTFVK AIGRYSAFSQ TECVEVQGEA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against IL20Rb. It has been selected for its ability to recognize IL20Rb in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: IL20Rb (MBS2017184)
Immunogen: IL20Rb (MBS2018629)
Matching Pairs
Unconjugated Antibody: IL20Rb (MBS2017184)
APC-CY7 Conjugated Antibody: IL20Rb (MBS2075324)
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Molecular Weight
16,945 Da
OMIM
AY358305 mRNA
3D Structure
ModBase 3D Structure for Q6UXL0
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant IL20Rb (Ala37~Glu290) expressed in E.coli.
Cross Reactivity
Human
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2075326
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-IL20Rb antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-IL20Rb antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-IL20Rb antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-IL20Rb Polyclonal Antibody – Cat# MBS2017184

Immunohistochemistry (IHC) of anti-IL20Rb antibody

DAB staining on fromalin fixed paraffin-embedded Liver tissue)
Rabbit Anti-IL20Rb Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2017184

Immunohistochemistry (IHC) of anti-IL20Rb antibody

DAB staining on IHC-P; Samples: Human Stomach Tissue)
Rabbit Anti-IL20Rb Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2017184

Other Notes

Small volumes of anti-IL20Rb antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL20Rb. It may not necessarily be applicable to this product.

NCBI GI #
40255073
NCBI GeneID
53833
NCBI Accession #
NP_653318.2
UniProt Primary Accession #
Q6UXL0
UniProt Secondary Accession #
Q6P438; Q8IYY5; Q8TAJ7; B4DL40
UniProt Related Accession #
Q6UXL0
GenBank Nucleotide #
NM_144717.3
NCBI Official Full Name
interleukin-20 receptor subunit beta
NCBI Official Synonym Full Names
interleukin 20 receptor subunit beta
NCBI Official Symbol
IL20RB
NCBI Official Synonym Symbols
DIRS1; FNDC6; IL-20R2
UniProt Protein Name
Interleukin-20 receptor subunit beta
UniProt Synonym Protein Names
Fibronectin type III domain containing 6; FNDC6; IL-20R2
Protein Family
Interleukin-20 receptor
UniProt Gene Name
IL20RB
UniProt Synonym Gene Names
DIRS1; IL-20 receptor subunit beta; IL-20R-beta; IL-20RB; FNDC6
NCBI Protein Information
interleukin-20 receptor subunit beta

NCBI Summary for IL20Rb

IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009]

UniProt Comments for IL20Rb

IL20RB: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24. Belongs to the type II cytokine receptor family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q22.3

Cellular Component: integral component of membrane; plasma membrane

Molecular Function: interleukin-10 receptor activity; interleukin-20 binding; protein binding

Biological Process: cytokine-mediated signaling pathway; homeostasis of number of cells within a tissue; immune response-inhibiting signal transduction; inflammatory response to antigenic stimulus; negative regulation of interferon-gamma production; negative regulation of interleukin-2 production; negative regulation of T cell proliferation; negative regulation of type IV hypersensitivity; positive regulation of interleukin-10 production; positive regulation of interleukin-4 production
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Research Articles on IL20Rb

1. Trabecular meshwork cells express IL-20 receptors; Mutation of the T104 residue in IL-20R2 leads to a reduction in STAT3 phosphorylation as well as decreased matrix metalloproteinase activity

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL20Rb antibody

 Reference Product  PubMed Publications
 IL20 antibody  >2 publications with IL20Rb and IL20

Pathways associated with anti-IL20Rb antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram

Diseases associated with anti-IL20Rb antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with IL20Rb and Inflammation

Organs/Tissues associated with anti-IL20Rb antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >1 publications with IL20Rb and Skin
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