• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Integrin Alpha D (ITGaD) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2017422
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2017422 is an antibody targeting ITGaD. Also known as Polyclonal Antibody to Integrin Alpha D (ITGaD). Reactive in Human. Host: Rabbit. More details

$205 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Integrin Alpha D (ITGaD), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Integrin Alpha D (ITGaD)
Product Gene Name
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- FD VSYKATLGDR MLMRASASSE NNKASSSKAT FQLELPVKYA VYTMISRQEE STKYFNFATS DEKKMKEAEH RYRVNNLSQR DLAISINFWV PVLLNGVAVW DVVMEAPSQS LPCVSERKPP QHSDFLTQIS RSPMLDCSIA DCLQFRCDVP SFSVQEELDF TLKGNLSFGW VRETLQKKVL VVSVAEITFD
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
1mg/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against ITGaD. It has been selected for its ability to recognize ITGaD in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: ITGaD (MBS2017422)
Immunogen: ITGaD (MBS2018702)
Matching Pairs
Unconjugated Antibody: ITGaD (MBS2017422)
APC-CY7 Conjugated Antibody: ITGaD (MBS2040346)
Molecular Weight
126,758 Da
OMIM
U37028 mRNA
3D Structure
ModBase 3D Structure for Q13349
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant ITGaD (Phe879~Asn1099) expressed in E.coli.
Cross Reactivity
Human
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2040348
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-ITGaD antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-ITGaD antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-ITGaD antibody

Western Blot: Sample: Human Serum.
Rabbit Anti-ITGaD Polyclonal Antibody – Cat# MBS2017422

Western Blot (WB) of anti-ITGaD antibody

Western Blot: Sample: Recombinant ITGaD, Human.
Rabbit Anti-ITGaD Polyclonal Antibody, Western Blot (WB) – Cat# MBS2017422

Immunohistochemistry (IHC) of anti-ITGaD antibody

DAB staining on IHC-P; Samples: Human Rectum Tissue.
Rabbit Anti-ITGaD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2017422

Immunohistochemistry (IHC) of anti-ITGaD antibody

DAB staining on IHC-P; Samples: Human Liver Tissue
Rabbit Anti-ITGaD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2017422

Immunohistochemistry (IHC) of anti-ITGaD antibody

DAB staining on IHC-P; Samples: Human Kidney Tissue
Rabbit Anti-ITGaD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2017422

Other Notes

Small volumes of anti-ITGaD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ITGaD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrin alpha-D isoform 1
NCBI Official Synonym Full Names
integrin subunit alpha D
NCBI Official Symbol
ITGAD
NCBI Official Synonym Symbols
ADB2; CD11D
UniProt Protein Name
Integrin alpha-D
UniProt Synonym Protein Names
ADB2; CD11 antigen-like family member D; Leukointegrin alpha D; CD_antigen: CD11d
Protein Family
UniProt Gene Name
ITGAD
NCBI Protein Information
integrin alpha-D

NCBI Summary for ITGaD

This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Show more

UniProt Comments for ITGaD

ITGAD: Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood- borne pathogens, particulate matter, and senescent erythrocytes from the blood. Belongs to the integrin alpha chain family.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: cell surface; integrin complex; plasma membrane

Molecular Function: metal ion binding

Biological Process: extracellular matrix organization; heterotypic cell-cell adhesion; immune response; integrin-mediated signaling pathway
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-ITGaD antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000