Calcium/Calmodulin Dependent Protein Kinase II Gamma (CAMK2g) Antibody – Rabbit Polyclonal

CAMK2G: a protein kinase of the CAMK2 family. A prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses that may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. The holoenzyme is composed of four different chains: alpha, beta, gamma, and delta. The different chains assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. May interact with BAALC, MPDZ, SYN1 and synGAP. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: CAMK group; CAMK2 family; EC 2.7.11.17; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 14|14 A3

Cellular Component: cytoplasm; membrane; neuron projection; postsynaptic density; sarcoplasmic reticulum

Molecular Function: ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; identical protein binding; kinase activity; nucleotide binding; protein homodimerization activity; protein kinase activity; protein serine/threonine kinase activity; transferase activity

Biological Process: calcium ion transport; cell differentiation; G1/S transition of mitotic cell cycle; multicellular organism development; nervous system development; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; phosphorylation; protein amino acid phosphorylation; protein autophosphorylation; protein oligomerization; response to hypoxia; response to oxidative stress