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Gamma-Synuclein (SNCG) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS202002

Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. All synucleins have in common a highly conserved alpha-helical… More details

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Product Overview

Product Name
Gamma-Synuclein (SNCG), Polyclonal Antibody
Full Product Name
Gamma-Synuclein antibody
Product Gene Name
Product Synonym Names
Synuclein gamma (breast cancer-specific protein 1); SNCG; BCSG1; PERSYN; PRSN; gamma-Synuclein; Persyn; Breast cancer-specific gene 1 protein; Synoretin; SR; gamma-synuclein; gamma synuclein; Synuclein; gamma (breast cancer-specific protein 1) BCSG 1; Breast cancer specific gene 1; Breast cancer specific gene 1 protein; Breast cancer specific protein 1; Gamma synuclein; SNCG protein; SR; Synuclein gamma
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
human
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
Purity/Purification
By protein-A affinity chromatography
Concentration
1mg/ml (lot specific)
Preparation and Storage
Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
13,331 Da
OMIM
AF010126 mRNA
3D Structure
ModBase 3D Structure for O76070
Antigen Species
Human
Immunogen
Recombinant human gamma-Synuclein (1-127aa)

Product Categories/Family for anti-SNCG antibody

Applications Tested/Suitable for anti-SNCG antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-SNCG antibody
WB: 1:500 ~ 2,000.
Recommended starting dilution is 1:1,000.

Western Blot (WB) of anti-SNCG antibody

The recombinant synuclein family (alpha-,beta- and gamma-) and the extracts of HT-29 (colon adenocarcinoma) cells were resolved by SDS-PAGE, transferred to PVDF membrane and probed with polyclonal anti-human gamma-synuclein (1:1,000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and the ECL detection system.
Rabbit Anti-SNCG Polyclonal Antibody – Cat# MBS202002

Product References and Citations for anti-SNCG antibody

Liu H. et. al. (2005) Cancer Res. 65, 7635-7643 Ji.H. et al. (1997)) Cancer Res. 57, 759-764 George, J.M. (2001) Genome Biol. 3, 3002.1-3002.6

Other Notes

Small volumes of anti-SNCG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNCG purchase

MBS202002 is an antibody targeting SNCG. Also known as Gamma-Synuclein antibody. Reactive in human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SNCG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
gamma-synuclein isoform 1
NCBI Official Synonym Full Names
synuclein gamma
NCBI Official Symbol
SNCG
NCBI Official Synonym Symbols
SR; BCSG1
UniProt Protein Name
Gamma-synuclein
UniProt Synonym Protein Names
Breast cancer-specific gene 1 protein; Persyn; Synoretin; SR
Protein Family
UniProt Gene Name
SNCG
UniProt Synonym Gene Names
BCSG1; PERSYN; PRSN; SR
NCBI Protein Information
gamma-synuclein

NCBI Summary for SNCG

This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010]

UniProt Comments for SNCG

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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