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Neutrophil Activating Protein 3 (NAP3) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2025778
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2025778 is an antibody targeting NAP3. Also known as Monoclonal Antibody to Neutrophil Activating Protein 3 (NAP3). Reactive in Rat. Host: Mouse. More details

$215 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Neutrophil Activating Protein 3 (NAP3), Monoclonal Antibody
Full Product Name
Monoclonal Antibody to Neutrophil Activating Protein 3 (NAP3)
Product Gene Name
anti-NAP3 antibody
Clonality
Monoclonal
Isotype
IgG2b Kappa
Clone Number
A5
Host
Mouse
Species Reactivity
Rat
Form/Format
Liquid
Purity/Purification
Affinity Chromatography
Concentration
1mg/ml (lot specific)
Specificity
The antibody is a mouse monoclonal antibody raised against NAP3. It has beenselected for its ability to recognize NAP3 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: NAP3 Clone #A5 (MBS2025778)
Immunogen: NAP3 (MBS2012378)
Matching Pairs
Unconjugated Antibody: NAP3 Clone #A5 (MBS2025778)
APC-CY7 Conjugated Antibody: NAP3 Clone #A5 (MBS2035790)
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Molecular Weight
10,249 Da
3D Structure
ModBase 3D Structure for P14095
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Organism Species
Rattus norvegicus (Rat)
Cross Reactivity
Rat
Conjugate
No Conjugate
Immunogen
Recombinant NAP3 (Ala25~Lys96) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2035794
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-NAP3 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-NAP3 antibody
Western blotting: 0.2-2ug/mL;1:500-5000
Immunohistochemistry: 5-20ug/mL;1:50-200
Immunocytochemistry: 5-20ug/mL;1:50-200
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-NAP3 antibody

Western Blot: Sample: Recombinant protein.
Mouse Anti-NAP3 Monoclonal Antibody – Cat# MBS2025778

Immunohistochemistry (IHC) of anti-NAP3 antibody

DAB staining on IHC-P; Samples: Rat Cerebrum Tissue)
Mouse Anti-NAP3 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2025778

Other Notes

Small volumes of anti-NAP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NAP3. It may not necessarily be applicable to this product.

NCBI GI #
13540652
NCBI GeneID
81503
NCBI Accession #
NP_110472.1
UniProt Primary Accession #
P14095
UniProt Related Accession #
P14095
GenBank Nucleotide #
NM_030845.1
NCBI Official Full Name
growth-regulated alpha protein
NCBI Official Synonym Full Names
C-X-C motif chemokine ligand 1
NCBI Official Symbol
Cxcl1
NCBI Official Synonym Symbols
Gro1; CINC-1
UniProt Protein Name
Growth-regulated alpha protein
UniProt Synonym Protein Names
C-X-C motif chemokine 1; Cytokine-induced neutrophil chemoattractant 1; CINC-1; Platelet-derived growth factor-inducible protein KC
UniProt Gene Name
Cxcl1
UniProt Synonym Gene Names
Cinc1; Gro; Scyb1; CINC-1
NCBI Protein Information
growth-regulated alpha protein

NCBI Summary for NAP3

acts as a neutrophil chemoattractant; may play a role in acute phase inflammatory response [RGD, Feb 2006]

UniProt Comments for NAP3

CXCL2: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14p22

Cellular Component: cell; extracellular space

Molecular Function: chemokine activity; CXCR chemokine receptor binding; growth factor activity

Biological Process: acute inflammatory response; defense response; elevation of cytosolic calcium ion concentration; G-protein coupled receptor signaling pathway; immune response; neutrophil chemotaxis; positive regulation of potassium ion transport; positive regulation of superoxide anion generation; regulation of cell proliferation; response to amphetamine; response to estradiol; response to gamma radiation; response to glucocorticoid stimulus; response to heat; response to lipopolysaccharide
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Research Articles on NAP3

1. Findings indicated that up-regulation of CXCL1 and CXCR2 might contribute to remifentanil-induce hypernociception via modulating spinal NR2B-containing NMDA receptor expression and phosphorylation in rats.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NAP3 antibody

 Reference Product  PubMed Publications
 Cxcl2 antibody  >569 publications with NAP3 and Cxcl2
 Ccl2 antibody  >545 publications with NAP3 and Ccl2
 Il8rb antibody  >236 publications with NAP3 and Il8rb
 Cxcl3 antibody  >100 publications with NAP3 and Cxcl3
 Cxcl6 antibody  >77 publications with NAP3 and Cxcl6
 Il6 antibody  >69 publications with NAP3 and Il6
 Cxcr4 antibody  >51 publications with NAP3 and Cxcr4
 Ccr2 antibody  >44 publications with NAP3 and Ccr2
 Cxcr3 antibody  >33 publications with NAP3 and Cxcr3
 Ppbp antibody  >21 publications with NAP3 and Ppbp

Pathways associated with anti-NAP3 antibody

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokines And Inflammatory Response (BioCarta) Pathway antibodies  Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram

Diseases associated with anti-NAP3 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1184 publications with NAP3 and Inflammation
 Necrosis Antibodies  >568 publications with NAP3 and Necrosis
 Disease Models, Animal Antibodies  >434 publications with NAP3 and Disease Models, Animal
 Lung Diseases Antibodies  >337 publications with NAP3 and Lung Diseases
 Cardiovascular Diseases Antibodies  >198 publications with NAP3 and Cardiovascular Diseases
 Lung Injury Antibodies  >175 publications with NAP3 and Lung Injury
 Pneumonia Antibodies  >116 publications with NAP3 and Pneumonia
 Wounds and Injuries Antibodies  >98 publications with NAP3 and Wounds and Injuries
 Reperfusion Injury Antibodies  >97 publications with NAP3 and Reperfusion Injury
 Fibrosis Antibodies  >91 publications with NAP3 and Fibrosis

Organs/Tissues associated with anti-NAP3 antibody

 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >36 publications with NAP3 and Pancreas
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