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Growth Differentiation Factor 9 (GDF9) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2026260
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2026260 is an antibody targeting GDF9. Also known as Polyclonal Antibody to Growth Differentiation Factor 9 (GDF9). Reactive in Rat. Host: Rabbit. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Growth Differentiation Factor 9 (GDF9), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Growth Differentiation Factor 9 (GDF9)
Product Gene Name
anti-GDF9 antibody
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- RGQKT LSSETKKPLT ASFNLSEYFR QFLFPQNECE LHDFRLSFSQ LKWDNWIVAP HRYNPRYCKG DCPRAVRHRY GSPVHTMVQN IIYEKLDPSV PRPSCVPGKY SPLSVLTIEP DGSIAYKEYE DMIATRCTCR
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Form/Format
Liquid
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against GDF9. It has beenselected for its ability to recognize GDF9 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: GDF9 (MBS2026260)
Immunogen: GDF9 (MBS2029080)
Matching Pairs
Unconjugated Antibody: GDF9 (MBS2026260)
APC-CY7 Conjugated Antibody: GDF9 (MBS2042255)
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Molecular Weight
49,682 Da
3D Structure
ModBase 3D Structure for Q9QYW4
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Fragment
GDF9 (Arg306~Arg440)
Organism Species
Rattus norvegicus (Rat)
Cross Reactivity
Rat
Conjugate
No Conjugate
Immunogen
Recombinant GDF9 (Arg306~Arg440) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2042257
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-GDF9 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-GDF9 antibody
Western blotting: 0.2-2ug/mL;1:250-2500
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-GDF9 antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-GDF9 Polyclonal Antibody – Cat# MBS2026260

Immunohistochemistry (IHC) of anti-GDF9 antibody

DAB staining on fromalin fixed paraffin- embedded Kidney tissue)
Rabbit Anti-GDF9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2026260

Other Notes

Small volumes of anti-GDF9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GDF9. It may not necessarily be applicable to this product.

NCBI GI #
81907140
NCBI Accession #
Q9QYW4
UniProt Primary Accession #
Q9QYW4
NCBI Official Full Name
Growth/differentiation factor-9
UniProt Protein Name
Growth differentiation factor 9
UniProt Synonym Protein Names
Growth differentiation factor 9
Protein Family
Growth/differentiation factor
UniProt Gene Name
Gdf9

UniProt Comments for GDF9

GDF9: Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells. Altered GDF9 function may be involved in ovarian disorders. Rare variants in GDF9 have been found in patients with premature ovarian failure and mothers of dizygotic twins. Belongs to the TGF-beta family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q22

Cellular Component: cytoplasm; extracellular space

Molecular Function: cytokine activity; growth factor activity; transforming growth factor beta receptor binding

Biological Process: BMP signaling pathway; cell development; negative regulation of cell growth; oocyte growth; positive regulation of cell proliferation; regulation of apoptosis; regulation of MAPK cascade
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GDF9 antibody

 Reference Product  PubMed Publications
 Bmp15 antibody  >424 publications with GDF9 and Bmp15
 Bmpr2 antibody  >39 publications with GDF9 and Bmpr2
 Smad2 antibody  >31 publications with GDF9 and Smad2
 Cyp19a1 antibody  >25 publications with GDF9 and Cyp19a1
 Fshr antibody  >23 publications with GDF9 and Fshr
 Zar1 antibody  >14 publications with GDF9 and Zar1
 Lhcgr antibody  >12 publications with GDF9 and Lhcgr
 Cyp17a1 antibody  >7 publications with GDF9 and Cyp17a1
 Fst antibody  >7 publications with GDF9 and Fst
 Kitlg antibody  >3 publications with GDF9 and Kitlg

Organs/Tissues associated with anti-GDF9 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >13 publications with GDF9 and Brain
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