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Transketolase (TKT) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2026339
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MBS2026339 is an antibody targeting TKT. Also known as Polyclonal Antibody to Transketolase (TKT). Reactive in Human. Host: Rabbit. More details

$215 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Transketolase (TKT), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Transketolase (TKT)
Product Gene Name
anti-TKT antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Affinity Chromatography
Concentration
1mg/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against TKT. It has beenselected for its ability to recognize TKT in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: TKT (MBS2026339)
Immunogen: TKT (MBS2030060)
Matching Pairs
Unconjugated Antibody: TKT (MBS2026339)
APC-CY7 Conjugated Antibody: TKT (MBS2079081)
Show more
Molecular Weight
68,814 Da
OMIM
X67688 mRNA
3D Structure
ModBase 3D Structure for P29401
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Fragment
TKT (Met1~Pro294)
Organism Species
Homo sapiens (Human)
Cross Reactivity
Human
Conjugate
No Conjugate
Immunogen
Recombinant TKT (Met1~Pro294) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2079083

Product Categories/Family for anti-TKT antibody

Knock-Out Validation Antibody
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-TKT antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-TKT antibody
Western blotting: 0.2-2ug/mL;1:250-2500
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-TKT antibody

Western Blot: Sample: Human A549 cell lysate; Primary Ab: 1ug/ml Rabbit Anti-Human TKT Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Rabbit Anti-TKT Polyclonal Antibody – Cat# MBS2026339

Western Blot (WB) of anti-TKT antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-TKT Polyclonal Antibody, Western Blot (WB) – Cat# MBS2026339

Immunohistochemistry (IHC) of anti-TKT antibody

DAB staining on IHC-P; Samples: Human Glioma Tissue)
Rabbit Anti-TKT Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2026339

Knockout Validation of anti-TKT antibody

Knockout Validation: Lane 1: Wild-type A549 cell lysate; Lane 2: TKT knockout A549 cell lysate; Predicted MW: 68,69kd Observed MW: 70kd Primary Ab: 1ug/ml Rabbit Anti-Human TKT Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047)
Rabbit Anti-TKT Polyclonal Antibody, Knockout Validation – Cat# MBS2026339

Other Notes

Small volumes of anti-TKT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TKT. It may not necessarily be applicable to this product.

NCBI GI #
4507521
NCBI GeneID
7086
NCBI Accession #
NP_001055.1
UniProt Primary Accession #
P29401
UniProt Secondary Accession #
Q8TBA3; Q96HH3; A8K089; B4DE31; E7EPA7
UniProt Related Accession #
P29401
GenBank Nucleotide #
NM_001064.3
NCBI Official Full Name
transketolase isoform 1
NCBI Official Synonym Full Names
transketolase
NCBI Official Symbol
TKT
NCBI Official Synonym Symbols
TK; TKT1; SDDHD; HEL107; HEL-S-48
UniProt Protein Name
Transketolase
Protein Family
Transketolase
UniProt Gene Name
TKT
UniProt Synonym Gene Names
TK
NCBI Protein Information
transketolase

NCBI Summary for TKT

This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]

UniProt Comments for TKT

TKT: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. Homodimer. Belongs to the transketolase family.

Protein type: Carbohydrate Metabolism - pentose phosphate pathway; EC 2.2.1.1; Transferase

Chromosomal Location of Human Ortholog: 3p21.1

Cellular Component: cytosol; extracellular exosome; myelin sheath; nuclear body; nuclear speck; nucleoplasm; peroxisome; vesicle

Molecular Function: cofactor binding; metal ion binding; protein binding; protein homodimerization activity; transketolase activity

Biological Process: glyceraldehyde-3-phosphate biosynthetic process; pentose-phosphate shunt; pentose-phosphate shunt, non-oxidative branch; regulation of growth; xylulose biosynthetic process

Disease: Short Stature, Developmental Delay, And Congenital Heart Defects
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Research Articles on TKT

1. reduced expression of transketolase in pyrimidine 5'-nucleotidase deficient patients

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TKT antibody

 Reference Product  PubMed Publications
 PKM2 antibody  >3 publications with TKT and PKM2
 ALDOA antibody  >3 publications with TKT and ALDOA
 RPE antibody  >3 publications with TKT and RPE
 RBKS antibody  >1 publications with TKT and RBKS
 UBC antibody  >1 publications with TKT and UBC
 FBP1 antibody  >1 publications with TKT and FBP1
 RPIA antibody  >1 publications with TKT and RPIA
 TALDO1 antibody  >1 publications with TKT and TALDO1

Pathways associated with anti-TKT antibody

 Products by Pathway  Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
 Insulin Effects Increased Synthesis Of Xylulose-5-Phosphate Pathway antibodies  Insulin Effects Increased Synthesis Of Xylulose-5-Phosphate Pathway Diagram
 Integration Of Energy Metabolism Pathway antibodies  Integration Of Energy Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram

Diseases associated with anti-TKT antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >21 publications with TKT and Carcinoma
 Kidney Diseases Antibodies  >9 publications with TKT and Kidney Diseases
 Nervous System Diseases Antibodies  >6 publications with TKT and Nervous System Diseases
 Liver Diseases Antibodies  >6 publications with TKT and Liver Diseases
 Congenital Abnormalities Antibodies  >5 publications with TKT and Congenital Abnormalities
 Inflammation Antibodies  >4 publications with TKT and Inflammation
 Liver Neoplasms Antibodies  >4 publications with TKT and Liver Neoplasms
 Fatty Liver Antibodies  >3 publications with TKT and Fatty Liver
 Hyperplasia Antibodies  >3 publications with TKT and Hyperplasia
 Necrosis Antibodies  >3 publications with TKT and Necrosis

Organs/Tissues associated with anti-TKT antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17 publications with TKT and Blood
 Eye Antibodies  >14 publications with TKT and Eye
 Liver Antibodies  >13 publications with TKT and Liver
 Kidney Antibodies  >13 publications with TKT and Kidney
 Connective Tissue Antibodies  >9 publications with TKT and Connective Tissue
 Mouth Antibodies  >8 publications with TKT and Mouth
 Bone Antibodies  >7 publications with TKT and Bone
 Brain Antibodies  >7 publications with TKT and Brain
 Lung Antibodies  >5 publications with TKT and Lung
 Heart Antibodies  >5 publications with TKT and Heart
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