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Integrin Alpha X (ITGaX) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2026838
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MBS2026838 is an antibody targeting ITGaX. Also known as Polyclonal Antibody to Integrin Alpha X (ITGaX). Reactive in Human, Rat. Host: Rabbit. More details

$210 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Integrin Alpha X (ITGaX), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Integrin Alpha X (ITGaX)
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
Liquid
Purity/Purification
Affinity Chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against ITGaX. It has beenselected for its ability to recognize ITGaX in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: ITGaX (MBS2026838)
Immunogen: ITGaX (MBS2031762)
Matching Pairs
Unconjugated Antibody: ITGaX (MBS2026838)
APC-CY7 Conjugated Antibody: ITGaX (MBS2052015)
Molecular Weight
127,829 Da
OMIM
M81695 mRNA
3D Structure
ModBase 3D Structure for P20702
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Fragment
ITGaX (Gln143~Ser344)
Organism Species
Homo sapiens (Human)
Cross Reactivity
Human
Conjugate
No Conjugate
Immunogen
Recombinant ITGaX (Gln143~Ser344) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2052017
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-ITGaX antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-ITGaX antibody
Western blotting: 0.5-2ug/mL;1:500-2000
Immunohistochemistry: 5-20ug/mL;1:50-200
Immunocytochemistry: 5-20ug/mL;1:50-200
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-ITGaX antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-ITGaX Polyclonal Antibody – Cat# MBS2026838

Immunohistochemistry (IHC) of anti-ITGaX antibody

DAB staining on fromalin fixed paraffin-embedded Liver tissue)
Rabbit Anti-ITGaX Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2026838

Other Notes

Small volumes of anti-ITGaX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ITGaX. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrin alpha-X isoform 2
NCBI Official Synonym Full Names
integrin subunit alpha X
NCBI Official Symbol
ITGAX
NCBI Official Synonym Symbols
CD11C; SLEB6
UniProt Protein Name
Integrin alpha-X
UniProt Synonym Protein Names
CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD_antigen: CD11c
Protein Family
UniProt Gene Name
ITGAX
UniProt Synonym Gene Names
CD11C
NCBI Protein Information
integrin alpha-X

NCBI Summary for ITGaX

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
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UniProt Comments for ITGaX

ITGAX: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Belongs to the integrin alpha chain family.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: cell surface; integrin complex; membrane; plasma membrane; secretory granule membrane

Molecular Function: metal ion binding; protein binding; receptor activity

Biological Process: cell adhesion; extracellular matrix organization; heterotypic cell-cell adhesion; integrin-mediated signaling pathway; leukocyte migration; neutrophil degranulation; organ morphogenesis

Disease: Systemic Lupus Erythematosus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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